# Challenges to overcome obstacles for pediatric donor heart availability

**Authors:** Norihide Fukushima

PMC · DOI: 10.1016/j.jhlto.2025.100395 · JHLT Open · 2025-09-24

## TL;DR

This paper discusses the ongoing challenges in making donor hearts available for children needing heart transplants.

## Contribution

The paper reviews past and current obstacles to pediatric donor heart availability.

## Key findings

- Pediatric heart transplantation remains the most effective option for severe heart conditions in children.
- Donor heart availability for children continues to be limited despite surgical advancements.
- The paper identifies challenges that have persisted over time in this area.

## Abstract

Although surgical techniques for congenital heart disease (CHD), including hypoplastic left heart syndrome, have progressively advanced, pediatric heart transplantation remains the most effective surgical option for complex CHD and cardiomyopathy with severe heart failure. However, donor heart availability for children continues to be limited. This article reviews past and current challenges in overcoming obstacles to pediatric donor heart availability.

## Linked entities

- **Diseases:** congenital heart disease (MONDO:0005453), hypoplastic left heart syndrome (MONDO:0004933), cardiomyopathy (MONDO:0004994), heart failure (MONDO:0005252)

## Full-text entities

- **Diseases:** cardiomyopathy (MESH:D009202), heart failure (MESH:D006333), hypoplastic left heart syndrome (MESH:D018636), CHD (MESH:D006330)

## Full text

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## References

61 references — full list in the complete paper: https://tomesphere.com/paper/PMC12550247/full.md

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Source: https://tomesphere.com/paper/PMC12550247