# Multi-Morbidity at Death and the US Disadvantage in Mortality

**Authors:** Magali Barbieri, Aline Désesquelles, Viviana Egidi, Luisa Frova, Francesco Grippo, France Meslé, Marilena Pappagallo, Sergi Trias-Llimós

PMC · DOI: 10.1007/s10680-025-09749-3 · European Journal of Population = Revue Européenne de Démographie · 2025-10-23

## TL;DR

The US has higher mortality rates than countries like France, Italy, and Spain, largely due to more people dying from multiple health conditions.

## Contribution

This study quantifies how multi-morbidity at death contributes to the US mortality disadvantage compared to peer countries.

## Key findings

- Multi-morbid processes account for 51-75% of the US life expectancy gap with Italy, Spain, and France.
- The US has disproportionately high rates of multi-morbidity at death compared to other high-income countries.
- Multi-morbidity is concentrated in the 20–85 age range in the US.

## Abstract

The US experiences significant excess mortality compared to peer countries. The literature indicates that a similar disadvantage affects morbidity and, more generally, the prevalence of risk factors for major diseases within the US population. In this study, we assess the impact of multi-morbidity at death on the mortality gap between the US and three other high-income countries with comparable data, namely France, Italy, and Spain. The study relies on an analysis of the multiple cause-of-death information available on all death certificates for 2017, used to classify morbid processes leading to death into three categories: simple, multi-morbid, and ill-defined. The results show disproportionately high rates of multi-morbid processes in the US compared with the other three countries. Multi-morbid processes contribute 51% of the US gap in life expectancy at birth with Italy, 73% with Spain, and 75% with France, with a particular concentration at ages 20–85 years. The prevalence of multi-morbid processes in the US is consistent with the hypothesis that multiple factors, rather than a single culprit, are at play in the disadvantage in mortality and it could explain, at least in part, the extraordinarily high cost of health care in this country.

## Full-text entities

- **Diseases:** Death (MESH:D003643), Morbidity (OMIM:614963)

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12549454/full.md

## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC12549454/full.md

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Source: https://tomesphere.com/paper/PMC12549454