# The Ross Procedure: Historical Context, Modern Outcomes, and the Road Ahead

**Authors:** Christian Eidson, Andrew Well, Joseph Turek, Carlos M. Mery, Ziv Beckerman

PMC · DOI: 10.1007/s11886-025-02296-7 · Current Cardiology Reports · 2025-10-23

## TL;DR

The Ross Procedure is a durable and effective aortic valve replacement option for children and adults, offering long-term benefits and restoring normal life expectancy.

## Contribution

This paper highlights the Ross Procedure's unique advantages and resurgence in modern clinical practice for aortic valve disease.

## Key findings

- The Ross Procedure uses living tissue that can grow, making it ideal for children and long-term durability.
- Long-term data shows the Ross Procedure has excellent outcomes and restores life expectancy to normal levels.
- It is a superior option for aortic valve replacement due to its low morbidity and mortality rates.

## Abstract

There remains no single perfect aortic valve replacement option in patients with aortic valve disease. In this manuscript, we will discuss the modern role of the Ross Procedure in children and adults with aortic valve disease.

Currently, the Ross procedure is the only established operation that allows replacement of the aortic valve with living, growing tissue. Use of the Ross procedure for aortic valve replacement has waxed and waned in recent decades. However, in recent years, with reports from long-term data series, interest has been redirected at the Ross procedure due to its excellent durability and freedom from long-term valvular morbidity and mortality.

In patients requiring aortic valve replacement, the Ross procedure offers excellent short- and long-term outcomes and can be tailored to specific pathologies and the needs of individual patients. In this patient population, it is the only intervention that restores life expectancy to that of the general population. The Ross procedure remains a superb intervention for the treatment of aortic valve disease in children and adults in the modern era and should be heavily considered as an option when aortic valve replacement is required.

## Linked entities

- **Diseases:** aortic valve disease (MONDO:0003803)

## Full-text entities

- **Diseases:** aortic valve disease (MESH:D000082862)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

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Source: https://tomesphere.com/paper/PMC12549422