# Incidental Diagnosis of Normal Pressure Hydrocephalus in Elderly Patients Presenting With Acute Neurological Illnesses: A Report of Two Cases

**Authors:** Kyaw Z Aung, Naw Eh Law Saw, Ei Ei Cho, Cherry Myint, Han Thant Thant

PMC · DOI: 10.7759/cureus.93025 · Cureus · 2025-09-23

## TL;DR

Two elderly patients with unrelated neurological issues were found to have normal pressure hydrocephalus, highlighting the need for early diagnosis and individualized care.

## Contribution

Reports two cases where normal pressure hydrocephalus was incidentally diagnosed during treatment for unrelated acute neurological conditions.

## Key findings

- Brain imaging for unrelated issues revealed ventriculomegaly and normal CSF pressure in both patients.
- Symptoms consistent with probable NPH were identified retrospectively in both cases.
- Early diagnosis enabled informed decision-making and supportive care planning despite no surgical intervention.

## Abstract

Normal pressure hydrocephalus (NPH) is a potentially reversible neurological condition in older adults characterized by gait disturbance, cognitive decline, and urinary incontinence, but its diagnosis is frequently delayed or missed, especially when patients present with other acute medical issues. We report two illustrative cases where probable NPH was incidentally detected during hospitalization for unrelated acute presentations. In both instances, brain imaging performed for other diagnostic purposes revealed ventriculomegaly, and subsequent cerebrospinal fluid (CSF) analysis confirmed normal opening pressure and composition. Further history revealed previously unaddressed symptoms consistent with probable NPH. Although surgical intervention was not pursued due to advanced age, comorbidities, and patient or family preferences, the diagnosis allowed for informed decision-making and supportive care planning.

These cases highlight how NPH may remain cryptic in elderly patients, especially when acute, self-limiting disorders dominate the clinical picture. They underscore the importance of maintaining a broad differential diagnosis and obtaining neuroimaging when chronic symptoms such as urinary incontinence, gait impairment, or cognitive decline are present, even when overshadowed by other diagnoses. Given that timely shunting can result in marked improvements in mobility, cognition, and bladder control in many patients, early identification is essential. At the same time, management of NPH must be individualized, taking into account patient age, comorbidities, surgical risks, and personal or family preferences. In both cases, while definitive intervention was not pursued, awareness of the diagnosis enabled informed shared decision-making and offered targeted long-term surveillance and supportive care.

## Linked entities

- **Diseases:** Normal pressure hydrocephalus (MONDO:0009366)

## Full-text entities

- **Diseases:** gait disturbance (MESH:D020233), ventriculomegaly (MESH:D006849), urinary incontinence (MESH:D014549), neurological condition (MESH:D019636), cognitive decline (MESH:D003072), Neurological Illnesses (MESH:D009461), gait impairment (MESH:D020234), NPH (MESH:D006850)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12548762/full.md

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Source: https://tomesphere.com/paper/PMC12548762