# Social and Behavioral Factors Associated With Diabetes in Southern California vs the US

**Authors:** Alexandra Descarpentrie, Sevan Esaian, Ben Allen, Juan Espinoza, Vishal Midya, Nathan Young, Tanya L. Alderete, Michael I. Goran

PMC · DOI: 10.1001/jamanetworkopen.2025.38377 · 2025-10-22

## TL;DR

The study compares diabetes risk factors in Southern California with national data, finding regional differences in social and behavioral factors like physical inactivity and food insecurity.

## Contribution

Identifies region-specific social and behavioral correlates of diabetes in Southern California and contrasts them with national patterns.

## Key findings

- Physical inactivity, lack of insurance, and food insecurity were key regional factors in Southern California.
- Nationally, obesity, food stamp use, older age, and minority status were more significant.
- The study highlights the need for regionally tailored diabetes interventions.

## Abstract

This cross-sectional study evaluates social and behavioral factors associated with diabetes in Southern California and contrasts these findings with national data.

What are the key social and behavioral factors associated with diagnosed diabetes in Southern California, and how do they differ from those observed at the national level?

This cross-sectional study of 5420 census tracts composed of approximately 18.5 million adults in Southern California identified physical inactivity, binge drinking, routine check-ups, lack of insurance, and food insecurity as key factors associated with diagnosed diabetes. While some factors overlapped nationally, obesity, food stamp participation, persons aged 65 years and older, and persons of racial or ethnic minority background were key factors nationwide but not regionally.

These findings point to possible regional differences in the factors associated with diabetes prevalence and highlight the need for further research to determine their significance and potential for guiding targeted interventions.

Diabetes disproportionately impacts communities across the US and in Southern California, where there is a large Hispanic population. Diabetes prevalence continues to increase, and more studies are needed to understand behaviors and socioecological factors contributing to diabetes risk regionally and nationally.

To identify social and behavioral correlates (SBC) of diabetes in Southern California and to contrast these findings with national data to help ensure that public health strategies are appropriately targeted and regionally responsive.

This ecological and cross-sectional study used modeled estimates from census tracts in Southern California and nationwide, drawing from the Centers for Disease Control and Prevention’s 2024 Population Level Analysis and Community Estimates (PLACES) dataset.

Based on PLACES data availability and prior evidence, 24 SBC were selected and were grouped into health outcomes and conditions, prevention, health risk behaviors, health-related social needs, and broader social determinants of health.

Diagnosed diabetes prevalence, also from the PLACES dataset, represented the percentage of adults ever diagnosed with diabetes by a health care professional, excluding gestational diabetes. A total of 24 indicators were tested for their association with diabetes prevalence using a gradient-boosted regression tree method.

In Southern California (5420 census tracts composed of approximately 18.5 million adults), diagnosed diabetes had a mean (SE) prevalence of 11.29% (0.06), ranging from 1.4% (0.05) to 33.6% (1.37), compared with 11.52% (0.02) nationally (62 480 tracts composed of approximately 253 million adults). In Southern California, leveraging an explainable machine learning approach, 5 key correlates were identified accounting for 67% of the estimate in the model: physical inactivity (31%), routine check-ups (14%), binge drinking (11%), lack of insurance (6%), and food insecurity (5%). While some key correlates overlapped regionally and nationally, their estimated contributions differed. Additionally, obesity, receipt of food stamps, being aged 65 years or older, and persons of ethnic or racial minority background (all except White, non-Hispanic) were key correlates nationally but not in Southern California.

In this cross-sectional study, key correlates of diagnosed diabetes in Southern California included physical inactivity, access to health care, and food insecurity, while nationally, obesity, food stamp participation, older age (≥65 years), and racial or ethnic minority status were also key. These findings point to possible regional differences in the factors linked to diabetes prevalence and highlight the need for further research to determine their significance and potential for guiding targeted interventions.

## Linked entities

- **Diseases:** diabetes (MONDO:0005015)

## Full-text entities

- **Diseases:** physical inactivity (MESH:C564765), obesity (MESH:D009765), binge drinking (MESH:D063425), gestational diabetes (MESH:D016640), Diabetes (MESH:D003920), food insecurity (MESH:D005517)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12547587/full.md

---
Source: https://tomesphere.com/paper/PMC12547587