# Tracheal adenoid cystic carcinoma: a case report

## TL;DR

This paper reports a rare case of tracheal adenoid cystic carcinoma and its successful treatment with surgery and radiotherapy.

## Contribution

The paper presents a detailed case report of tracheal adenoid cystic carcinoma with successful multidisciplinary treatment and one-year follow-up.

## Key findings

- The patient had a 32-mm tracheal tumor with 80% stenosis, diagnosed as TACC via bronchoscopy and biopsy.
- Surgery and adjuvant radiotherapy achieved clear margins and no recurrence at one-year follow-up.
- TACC requires early diagnosis and radical treatment for improved prognosis.

## Abstract

Primary malignant tumors of the trachea are extremely rare, representing only 0.2% of all respiratory tract tumors. Among them, adenoid cystic carcinoma (ACC) is the second most frequent histological type. Due to its slow growth and misleading symptoms, diagnosis is often delayed.

We report the case of a 42-year-old male, chronic smoker, who presented with progressive dyspnea and mild hemoptysis. Chest CT revealed a 32-mm expansive lesion of the cervical trachea causing 80% stenosis. Bronchoscopy confirmed an intratracheal mass, and biopsy established the diagnosis of tracheal adenoid cystic carcinoma (TACC).

The patient underwent crico-tracheal resection with total thyroidectomy and central neck dissection. Histopathology confirmed TACC with perineural and angiolymphatic invasion, as well as thyroid gland infiltration, but clear surgical margins. Adjuvant radiotherapy was delivered using volumetric modulated arc therapy to a total dose of 60 Gy.

The postoperative course was uneventful, and the patient recovered well. At one-year follow-up, both CT and bronchoscopy confirmed an unobstructed trachea with no evidence of local recurrence or distant metastasis.

TACC is an uncommon and challenging malignancy requiring multidisciplinary management. Radical surgery with adjuvant radiotherapy remains the optimal strategy to achieve local control, particularly in cases with perineural invasion. Early diagnosis and complete resection are key to improving long-term prognosis.