# Sister Mary Joseph's Nodule Revealing Klatskin's Cholangiocarcinoma at the Yalgado Ouedraogo University Hospital: Case Report and Literature Review

**Authors:** Lawagoulé Joseph Emile Ky, Eric Hervé Mourfou, Abdoul Fatao Maïga, Daouda Sangaré, Damien Marcel Traoré, Saïdou Santi, Madina Koanda, Alimata Sanfo, Delphine Napon/Zongo, Aboubacar Coulibaly, Kounpiélimé Sosthène Somda, Arsène Roger Sombié

PMC · DOI: 10.1002/ccr3.71337 · Clinical Case Reports · 2025-10-22

## TL;DR

A rare case of umbilical metastasis (Sister Mary Joseph nodule) revealed advanced cholangiocarcinoma at a university hospital.

## Contribution

This paper presents a rare case linking Sister Mary Joseph nodule to Klatskin's cholangiocarcinoma.

## Key findings

- Sister Mary Joseph nodule was found to be a sign of advanced Klatskin's cholangiocarcinoma.
- The case highlights the importance of skin biopsy and imaging when such nodules are detected.

## Abstract

Umbilical cutaneous metastases of abdomino‐pelvic tumors are rare. They are known as Sister Mary Joseph nodules. The presence of this nodule indicates an advanced cancerous lesion and is associated with a poor prognosis. Because of its rarity, the Sister Mary Joseph nodule can go unnoticed. Its discovery should prompt a skin biopsy and abdomino‐pelvic cross‐sectional imaging. The occurrence of a Sister Mary Joseph nodule secondary to cholangiocarcinoma is rare. The aim of our work was to present a case of umbilical cutaneous metastasis revealing a Klatskin's cholangiocarcinoma in the Hepato‐gastroenterology department of the Yalgado Ouedraogo University Hospital (CHU YO).

## Linked entities

- **Diseases:** cholangiocarcinoma (MONDO:0019087)

## Full-text entities

- **Diseases:** metastases of (MESH:D009362), Sister Mary Joseph nodule (MESH:D058288), cancerous lesion (MESH:D009369), cholangiocarcinoma (MESH:D018281), Klatskin's Cholangiocarcinoma (MESH:D018285), abdomino-pelvic tumors (MESH:D010386)

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12544702/full.md

## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC12544702/full.md

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Source: https://tomesphere.com/paper/PMC12544702