# Solitary Testicular Metastasis From Prostate Cancer Treated With Orchiectomy: A Rare Case of Isolated Recurrence After Salvage Radiotherapy

**Authors:** Moritz Gutjahr-Holland, Shreya Armstrong

PMC · DOI: 10.1155/criu/7042029 · Case Reports in Urology · 2025-10-15

## TL;DR

A rare case of prostate cancer spreading to one testicle was successfully treated with surgery after radiation therapy.

## Contribution

This case report highlights a rare metastasis pattern and treatment response in prostate cancer.

## Key findings

- Prostate cancer metastasized to a single testicle after salvage radiation therapy.
- Orchiectomy led to a rapid decrease in PSA levels in the patient.

## Abstract

Prostate cancer (PCa) is the most commonly diagnosed cancer in Australia with almost 25,000 cases being diagnosed each year. Treatment for PCa varies depending on stage, patient preferences and the general health of the patient. PCa most commonly spreads to lymph nodes and bones. We present a case of a 66-year-old male who presented with PSA elevation post salvage radiation and was diagnosed with oligometastatic PCa to the right testis. This patient subsequently underwent a right orchidectomy resulting in a rapid fall in PSA.

## Linked entities

- **Diseases:** prostate cancer (MONDO:0005159)

## Full-text entities

- **Genes:** NPEPPS (aminopeptidase puromycin sensitive) [NCBI Gene 9520] {aka AAP-S, MP100, PSA}
- **Diseases:** PCa (MESH:D011471), Testicular Metastasis (MESH:D009362), cancer (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12543520/full.md

## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC12543520/full.md

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Source: https://tomesphere.com/paper/PMC12543520