# First Described Case of Infective Endocarditis Involving the Pulmonary Valve Caused by Moraxella catarrhalis

**Authors:** P. Karamani, E. Christopoulou, A. Negash, C. Charalambous, G. M. Georgiou, I. Tzanavaros, G. Miltiadous

PMC · DOI: 10.1155/crdi/1815282 · Case Reports in Infectious Diseases · 2025-10-15

## TL;DR

A rare case of infective endocarditis caused by Moraxella catarrhalis at the pulmonary valve is described, highlighting diagnostic challenges and the role of cardiac CT.

## Contribution

First described case of M. catarrhalis causing prosthetic pulmonary valve infective endocarditis.

## Key findings

- M. catarrhalis can cause prosthetic pulmonary valve infective endocarditis.
- Cardiac CT is essential for diagnosing IE when TOE results are negative.
- Right-sided IE may be missed by TOE, especially with prosthetic valves.

## Abstract

Moraxella catarrhalis, once considered a component of the normal human flora of the upper respiratory tract, is now recognized as a true pathogen and, rarely, a cause of infective endocarditis (IE).

We describe a rare case of a 36-year-old woman who presented with respiratory symptoms and was initially misdiagnosed with pneumonia and M. catarrhalis bacteremia. No vegetations were seen on transesophageal echocardiogram (TOE) imaging. However, further investigation with cardiac computed tomography (CT) revealed prosthetic pulmonary valve IE caused by M. catarrhalis, which also resulted in pulmonary abscesses.

This case highlights the importance of considering M. catarrhalis as a true pathogen in invasive disease, including prosthetic pulmonary valve IE. It also demonstrates the limitations of negative TOE findings in the evaluation of right-sided IE, particularly when prosthetic valves are involved. Cardiac CT is crucial when TOE results are negative but clinical suspicion for prosthetic right-sided IE remains high, as it aids in diagnosing both the infection and its perivalvular or periprosthetic complications.

## Linked entities

- **Diseases:** infective endocarditis (MONDO:0000565), pneumonia (MONDO:0005249)
- **Species:** Moraxella catarrhalis (taxon 480)

## Full-text entities

- **Diseases:** M. catarrhalis bacteremia (MESH:D016470), IE (MESH:D004696), pulmonary abscesses (MESH:D008169), infection (MESH:D007239), pneumonia (MESH:D011014), invasive (MESH:D009361)
- **Species:** Moraxella catarrhalis (species) [taxon 480], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12543443/full.md

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Source: https://tomesphere.com/paper/PMC12543443