# Consciousness and spintronic coherence in microtubules

**Authors:** Majid Beshkar

PMC · DOI: 10.1080/19420889.2025.2576334 · Communicative & Integrative Biology · 2025-10-21

## TL;DR

The paper proposes that quantum coherence in microtubules within the brain could be the basis for consciousness.

## Contribution

It introduces the QBIT theory, linking microtubule spintronic coherence to the generation of conscious experience.

## Key findings

- Microtubules in the axon initial segment can exhibit quantum coherence due to spintronic and memristive effects.
- Spontaneous coherence in microtubules is proposed as the basis for generating a micro-consciousness (a quale).
- Synchronized activity across multiple brain regions could produce macro-consciousness as a unified experience.

## Abstract

Microtubules are nanoscale spintronic oscillators with memristive properties. Spintronic and memristive effects, together with some unique conditions found in the axon initial segment (AIS), allow quantum coherence to emerge spontaneously in a population of microtubules located within the AIS. According to the QBIT theory, the spontaneous emergence of coherence in a population of microtubules is the necessary and sufficient condition for the generation of a micro-consciousness (a quale) by the brain. Simultaneous generation of multiple qualia by synchronized activity in different parts of the cerebral cortex gives rise to the appearance of a macro-consciousness: a seemingly unified subjective experience.

## Full-text entities

- **Genes:** IS1 (Adolescent idiopathic scoliosis) [NCBI Gene 260402] {aka AIS, AIS1}, RMDN1 (regulator of microtubule dynamics 1) [NCBI Gene 51115] {aka CGI-90, FAM82B, RMD-1, RMD1}, NDEL1 (nudE neurodevelopment protein 1 like 1) [NCBI Gene 81565] {aka EOPA, MITAP1, NDE1L1, NDE2, NUDEL}, MAPRE3 (microtubule associated protein RP/EB family member 3) [NCBI Gene 22924] {aka EB3, EBF3, EBF3-S, RP3}, ALB (albumin) [NCBI Gene 213] {aka FDAHT, HSA, PRO0883, PRO0903, PRO1341}, ANK3 (ankyrin 3) [NCBI Gene 288] {aka ANKYRIN-G, MRT37}, LYZ (lysozyme) [NCBI Gene 4069] {aka AMYLD5, LYZF1, LZM}, MAPT (microtubule associated protein tau) [NCBI Gene 4137] {aka DDPAC, FTD1, FTDP-17, MAPTL, MSTD, MTBT1}, LHX2 (LIM homeobox 2) [NCBI Gene 9355] {aka LH2, hLhx2}, MAPRE1 (microtubule associated protein RP/EB family member 1) [NCBI Gene 22919] {aka EB1}, CAMK2G (calcium/calmodulin dependent protein kinase II gamma) [NCBI Gene 818] {aka CAMK, CAMK-II, CAMKG, MRD59}, TRIM46 (tripartite motif containing 46) [NCBI Gene 80128] {aka GENEY, TRIFIC}
- **Diseases:** allodynia (MESH:D006930)
- **Chemicals:** hydrogen (MESH:D006859), ytterbium (MESH:D015018), polyalanine (MESH:C019529), titanium dioxide (MESH:C009495), Carbon nanotubes (MESH:D037742), Bose-Einstein condensate (-), silicon (MESH:D012825), sodium (MESH:D012964), diamond (MESH:D018130), tetraphenylporphyrin (MESH:C409084), peptides (MESH:D010455), voltage (MESH:C069547), carbon (MESH:D002244), GTP (MESH:D006160), oxygen (MESH:D010100)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12542615/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12542615/full.md

## References

108 references — full list in the complete paper: https://tomesphere.com/paper/PMC12542615/full.md

---
Source: https://tomesphere.com/paper/PMC12542615