# Oncological allograft failure for humerus reconstruction: the ‘strategic’ vascularized fibula

**Authors:** Alessia Pagnotta, Virginia Maria Formica, Stefano Gumina, Francesca Romana Grippaudo, Carmine Zoccali

PMC · DOI: 10.1080/23320885.2025.2572833 · Case Reports in Plastic Surgery & Hand Surgery · 2025-10-21

## TL;DR

This paper discusses using a vascularized fibula graft to improve outcomes in humerus reconstruction after allograft failure in cancer patients.

## Contribution

The study presents a strategic use of FVFG in complex humeral defects following allograft failure in oncology.

## Key findings

- Three cancer patients with allograft failure were successfully treated with FVFG.
- FVFG preserved upper limb function in cases of complex humeral defects.
- The technique shows promise for reducing complications in humeral reconstruction.

## Abstract

The allograft for humeral reconstruction is a widely used technique in oncology but complication rates are high and Free Vascularized Fibula Graft (FVFG) represents a “strategic” solution to preserve satisfactory upper limb function. We treated 3 cancer patients with allograft failures and FVFG was used to reconstruct complex humeral defects.

## Linked entities

- **Diseases:** cancer (MONDO:0004992)

## Full-text entities

- **Diseases:** humeral (MESH:D006810), cancer (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12541914/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12541914/full.md

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Source: https://tomesphere.com/paper/PMC12541914