# Chinese expert consensus on the diagnosis and treatment of plasma cell leukemia（2025）

## TL;DR

This paper presents a Chinese expert consensus on diagnosing and treating plasma cell leukemia, a rare and aggressive cancer, to improve patient outcomes.

## Contribution

Provides a systematic clinical guideline for PCL diagnosis, treatment, and follow-up in China.

## Key findings

- PCL is a rare and highly aggressive plasma cell malignancy with rapid clinical progression and poor prognosis.
- The consensus offers standardized recommendations for diagnosis, risk assessment, treatment strategies, and follow-up management.
- The goal is to improve survival rates and quality of life for patients through standardized care.

## Abstract

浆细胞白血病（PCL）是一种少见且侵袭性极高的浆细胞恶性肿瘤，临床进展迅速，预后极差。本共识旨在为临床医师提供PCL诊断标准、风险评估、治疗策略（包括初始治疗、造血干细胞移植和新型药物应用）及随访管理的系统建议，以规范诊疗流程，提高患者的生存率与生活质量。