# Construction and Validation of an Automatic Segmentation Method for Respiratory Sound Time Labels

**Authors:** Jian Fan, Haoran Ni, Xiulan Chen, Yulin Duan, Wanmin Wang, Fan Xu, Yan Shang

PMC · DOI: 10.1111/crj.70124 · The Clinical Respiratory Journal · 2025-10-21

## TL;DR

This paper presents a new method for automatically segmenting respiratory sounds into inhale and exhale phases to improve disease diagnosis.

## Contribution

A novel digital visualization method for respiratory sound segmentation and disease comparison is developed and validated.

## Key findings

- The method successfully segments respiratory sounds into inhale and exhale phases.
- Amplitude features differ among various respiratory diseases.
- The platform provides objective evidence for auscultation and visual display of breath sounds.

## Abstract

In the field of respiratory system diseases, the utilization of respiratory sounds in auscultation plays a crucial role in the specific disease diagnosis. However, during the process of auscultation, the personal experiences and environmental factors may affect the decision making, leading to diagnostic errors. Therefore, to accurately and effectively obtain and analyze respiratory sounds can be positively contribute to the diagnosis and treatment of respiratory system diseases.

Our aim was to develop an analytical method for the visualization and digitization of respiratory audio data, and to validate its capability to differentiate between various background diseases.

This study collected the respiratory sounds of patients admitted to the Department of General Medicine of Shanghai Changhai Hospital from June to December 2023. After strict screening according to the inclusion and exclusion criteria, a total of 84 patients were included. The research process includes using an electronic stethoscope to collect lung sounds from patients in a quiet environment. The patients expose their chests and lie flat. Sound data are collected at six landmark positions on the chest. The collected audio files are imported into an analysis tool for segmentation and feature extraction. Specific analysis methods include distinguishing heart sounds and respiratory sounds, segmenting respiratory sounds, determining the inspiratory and expiratory phases, and using a tool developed by the team for automatic segmentation encoding.

We standardized the respiratory sounds of 84 patients and segmented multiple respiratory cycles. Following the localization and segmentation of the respiratory cycles based on label information, we calculated the average and standard deviation of the amplitude features for each segment of the respiratory cycle. The results indicated differences among various diseases.

The robust algorithm platform is capable of segmenting the respiratory sounds into inhale and exhale phases accordingly, then comparing the difference between different background diseases. This method provides objective evidence for the auscultation of respiratory sounds and visual display of breath sounds.

A digital visualization method segments respiratory sounds into inhale/exhale phases, enabling robust analysis and comparison across diseases. It provides objective auscultation evidence and visual breath sound displays.

## Full-text entities

- **Diseases:** respiratory system diseases (MESH:D015619)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12540928/full.md

## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12540928/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12540928/full.md

---
Source: https://tomesphere.com/paper/PMC12540928