# Clinical outcome of Two Minute Walk Test after return to run program in IDEO users: a retrospective study

## TL;DR

This study shows that combining a special orthosis with a 4-week running rehab program significantly improves walking ability in people with severe lower limb injuries.

## Contribution

The study demonstrates the effectiveness of combining IDEO with RTR for improving mobility in patients with lower limb injuries.

## Key findings

- Patients using IDEO alone walked significantly farther than without IDEO.
- The combination of IDEO and RTR led to the greatest improvement in walking distance.
- Improvements exceeded clinically meaningful thresholds for the 2MWT.

## Abstract

To investigate clinical improvement in persons with severe musculoskeletal injuries following a 4-week high intensity sports-based return to run rehabilitation therapy program (RTR) combined with use of an Intrepid Dynamic Exoskeletal Orthosis (IDEO).

41 persons (37 male and 4 female) with lower limb musculoskeletal injuries undergoing treatment and rehabilitation at the Center for the Intrepid were included in the retrospective cohort study.

Retrospective analysis of clinical data was used to identify changes in Two Minute Walk Test (2MWT) outcomes in patients with lower limb musculoskeletal injuries without the IDEO, with the IDEO alone and after IDEO + RTR. A repeated measures ANOVA was used to examine differences in distance walked across the three groups (NO IDEO, IDEO alone, and IDEO + RTR). Bonferroni post-hoc analysis was performed, and a level of significance was set at 0.05.

A statistically significant difference in distance walked between all groups was observed (p < 0.001). Patients' mean distance walked using the IDEO alone (179 m, p < 0.001) and IDEO + RTR (208 m, p < 0.001) increased significantly compared to NO IDEO (152 m, p < 0.001). These differences surpass the Minimal Clinically Important Difference (37.2 m) and the Minimal Detectable Change (34.3 m) for the 2MWT in the limb loss population.

These data suggest the potential benefit of the combination of IDEO + RTR improved walking in patients with lower limb musculoskeletal injuries and suggest the 2MWT may be a meaningful, simple measure to detect improvement in function.