# Integrated Multimodal Imaging for Transvenous Transpulmonary Atrial Pacing Lead Implantation in Fontan Patient

**Authors:** Miranda J. Flores, Lauren Sell, Anjan S. Batra, Sanjay P. Sinha, Gira S. Morchi, Joanne P. Starr, Anthony C. McCanta

PMC · DOI: 10.1016/j.jaccas.2025.105286 · JACC Case Reports · 2025-10-01

## TL;DR

This paper describes a new method using combined imaging techniques to safely implant pacemaker leads in patients with a specific heart condition.

## Contribution

The novel approach integrates multiple imaging modalities for transvenous transpulmonary lead placement in high-risk Fontan patients.

## Key findings

- Multimodal imaging enabled successful transvenous transpulmonary lead placement in an extracardiac Fontan patient.
- Integrated imaging techniques can improve safety and success in high-risk Fontan patients.
- This approach offers an alternative to traditional epicardial lead placement with lower long-term risks.

## Abstract

Pacemaker placement in Fontan patients is challenging owing to lack of venous continuity with the atrial and ventricular myocardium. The standard epicardial approach is complicated by the need for repeat sternotomy or thoracotomy as well as the overall long-term risk of lead failure. Transvenous lead implant has been described, but this requires transpulmonary or transbaffle puncture, which have risks of bleeding and pericardial effusion.

We describe a case in which multimodal imaging with fluoroscopy, computed tomography, intracardiac echocardiography, and three-dimensional electroanatomical mapping were combined to perform successful transvenous transpulmonary epicardial atrial lead placement in an extracardiac Fontan patient with protein-losing enteropathy.

This approach can be considered as an alternative to epicardial lead placement in Fontan patients who are at moderate to high risk with the standard epicardial approach.

Congenital heart patients with extracardiac Fontan repairs pose unique technical challenges to pacemaker implantation given the lack of venous continuity with the myocardium. The transvenous, transpulmonary approach to epicardial atrial lead placement can be considered in high-risk extracardiac Fontan patients, using integrated multimodal imaging techniques to maximize safety and success.

## Linked entities

- **Diseases:** protein-losing enteropathy (MONDO:0009174)

## Full-text entities

- **Diseases:** bleeding (MESH:D006470), protein-losing enteropathy (MESH:D011504), pericardial effusion (MESH:D010490)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

9 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12540278/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12540278/full.md

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Source: https://tomesphere.com/paper/PMC12540278