# Meeting abstracts of the GISM Annual Meeting 2025

**Authors:** Enrico Ragni, Enrico Lucarelli, Stefano Grolli, Antonietta Rosa Silini, Valentina Grespi, Ivana Ferrero, Luisa Pascucci, Michela Pozzobon

PMC · DOI: 10.20517/evcna.2025.53 · Extracellular Vesicles and Circulating Nucleic Acids · 2025-08-04

## Full-text entities

- **Genes:** CD9 (CD9 molecule) [NCBI Gene 928] {aka BTCC-1, DRAP-27, MIC3, MRP-1, TSPAN-29, TSPAN29}, ATHS (atherosclerosis susceptibility (lipoprotein associated)) [NCBI Gene 470] {aka ALP}, FTH1 (ferritin heavy chain 1) [NCBI Gene 2495] {aka FHC, FTH, FTHL6, HFE5, NBIA9, PIG15}, FMOD (fibromodulin) [NCBI Gene 2331] {aka FM, SLRR2E}, SEMA4D (semaphorin 4D) [NCBI Gene 10507] {aka A8, BB18, C9orf164, CD100, COLL4, GR3}, TNF (tumor necrosis factor) [NCBI Gene 7124] {aka DIF, IMD127, TNF-alpha, TNFA, TNFSF2, TNLG1F}, PTPRC (protein tyrosine phosphatase receptor type C) [NCBI Gene 5788] {aka B220, CD45, CD45R, GP180, IMD105, L-CA}, ITGA5 (integrin subunit alpha 5) [NCBI Gene 3678] {aka CD49e, FNRA, VLA-5, VLA5A}, GP9 (glycoprotein IX platelet) [NCBI Gene 2815] {aka CD42a, GPIX}, CD63 (CD63 molecule) [NCBI Gene 967] {aka AD1, HOP-26, ME491, MLA1, OMA81H, Pltgp40}, SOX2 (SRY-box transcription factor 2) [NCBI Gene 6657] {aka ANOP3, MCOPS3}, VCAN (versican) [NCBI Gene 1462] {aka CSPG2, ERVR, GHAP, PG-M, WGN, WGN1}, KRT10 (keratin 10) [NCBI Gene 3858] {aka BCIE, BIE, CK10, EHK, EHK2, EHK2A}, CD44 (CD44 molecule (IN blood group)) [NCBI Gene 960] {aka CDW44, CSPG8, ECM-III, ECMR-III, H-CAM, HCELL}, NT5E (5'-nucleotidase ecto) [NCBI Gene 4907] {aka CALJA, CD73, E5NT, NT, NT5, NTE}, Amh (anti-Mullerian hormone) [NCBI Gene 11705] {aka MIS}, VTN (vitronectin) [NCBI Gene 7448] {aka V75, VN, VNT}, IL1B (interleukin 1 beta) [NCBI Gene 3553] {aka IL-1, IL1-BETA, IL1F2, IL1beta}, MMP13 (matrix metallopeptidase 13) [NCBI Gene 4322] {aka CLG3, MANDP1, MDST, MMP-13}, VIM (vimentin) [NCBI Gene 7431], CD81 (CD81 molecule) [NCBI Gene 975] {aka CVID6, S5.7, TAPA1, TSPAN28}, PECAM1 (platelet and endothelial cell adhesion molecule 1) [NCBI Gene 5175] {aka CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM}, NCAM1 (neural cell adhesion molecule 1) [NCBI Gene 4684] {aka CD56, MSK39, NCAM}, RP1 (RP1 axonemal microtubule associated) [NCBI Gene 6101] {aka DCDC4A, ORP1}, COL2A1 (collagen type II alpha 1 chain) [NCBI Gene 1280] {aka ACG2, ANFH, ANFH1, AOM, COL11A3, EDMMD}, SDHA (succinate dehydrogenase complex flavoprotein subunit A) [NCBI Gene 6389] {aka CMD1GG, FP, MC2DN1, NDAXOA, PGL5, PPGL5}, SDHB (succinate dehydrogenase complex iron sulfur subunit B) [NCBI Gene 6390] {aka CWS2, IP, MC2DN4, PGL4, PPGL4, SDH}, COX2 (cytochrome c oxidase subunit II) [NCBI Gene 4513] {aka COII, MTCO2}, BMP2 (bone morphogenetic protein 2) [NCBI Gene 650] {aka BDA2, BMP2A, SSFSC, SSFSC1}, IDO1 (indoleamine 2,3-dioxygenase 1) [NCBI Gene 3620] {aka IDO, IDO-1, INDO}, FAP (fibroblast activation protein alpha) [NCBI Gene 2191] {aka DPPIV, FAPA, FAPalpha, SIMP}, AWAT2 (acyl-CoA wax alcohol acyltransferase 2) [NCBI Gene 158835] {aka ARAT, DC4, DGAT2L4, MFAT, WS}, PPARGC1A (PPARG coactivator 1 alpha) [NCBI Gene 10891] {aka LEM6, PGC-1(alpha), PGC-1alpha, PGC-1v, PGC1, PGC1A}, ACTA1 (actin alpha 1, skeletal muscle) [NCBI Gene 58] {aka ACTA, ASMA, CFTD, CFTD1, CFTDM, CMYO2A}, CXCL8 (C-X-C motif chemokine ligand 8) [NCBI Gene 3576] {aka GCP-1, GCP1, IL8, LECT, LUCT, LYNAP}, LGALS1 (galectin 1) [NCBI Gene 3956] {aka GAL1, GBP}, POU5F1 (POU class 5 homeobox 1) [NCBI Gene 5460] {aka OCT3, OCT4, OCT4Borf1, OTF-3, OTF3, OTF4}, NFKB1 (nuclear factor kappa B subunit 1) [NCBI Gene 4790] {aka CVID12, EBP-1, KBF1, NF-kB, NF-kB1, NF-kappa-B1}, LHX2 (LIM homeobox 2) [NCBI Gene 9355] {aka LH2, hLhx2}, RTN4 (reticulon 4) [NCBI Gene 57142] {aka ASY, NI220/250, NOGO, NOGOA, NOGOB, NSP}, VEGFA (vascular endothelial growth factor A) [NCBI Gene 7422] {aka L-VEGF, MVCD1, VEGF, VPF}, LUM (lumican) [NCBI Gene 4060] {aka LDC, SLRR2D}, CD34 (CD34 molecule) [NCBI Gene 947], IL18 (interleukin 18) [NCBI Gene 3606] {aka IGIF, IL-18, IL-1g, IL1F4}, CCN2 (cellular communication network factor 2) [NCBI Gene 1490] {aka CTGF, HCS24, IBP-8, IGFBP8, KMD, NOV2}, TNF (tumor necrosis factor) [NCBI Gene 280943] {aka TNF-a, TNF-alpha, TNFa}, NEFL (neurofilament light chain) [NCBI Gene 4747] {aka CMT1F, CMT2E, CMTDIG, NF-L, NF68, NFL}, SOD2 (superoxide dismutase 2) [NCBI Gene 6648] {aka GC1, GClnc1, IPO-B, IPOB, MNSOD, MVCD6}, TLR4 (toll like receptor 4) [NCBI Gene 281536], POSTN (periostin) [NCBI Gene 10631] {aka OSF-2, OSF2, PDLPOSTN, PN}, THY1 (Thy-1 cell surface antigen) [NCBI Gene 7070] {aka CD90, CDw90}, NLRP3 (NLR family pyrin domain containing 3) [NCBI Gene 114548] {aka AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1}, COL11A1 (collagen type XI alpha 1 chain) [NCBI Gene 1301] {aka CO11A1, COLL6, DFNA37, STL2}, TP63 (tumor protein p63) [NCBI Gene 8626] {aka AIS, B(p51A), B(p51B), EEC3, KET, LMS}, SEMA3A (semaphorin 3A) [NCBI Gene 10371] {aka COLL1, HH16, Hsema-I, Hsema-III, SEMA1, SEMAD}, TFRC (transferrin receptor) [NCBI Gene 7037] {aka CD71, IMD46, T9, TFR, TFR1, TR}, IFNG (interferon gamma) [NCBI Gene 281237], SOX9 (SRY-box transcription factor 9) [NCBI Gene 6662] {aka CMD1, CMPD1, ENH13, SRA1, SRXX2, SRXY10}, MMP9 (matrix metallopeptidase 9) [NCBI Gene 4318] {aka CLG4B, GELB, MANDP2, MMP-9}, IL6 (interleukin 6) [NCBI Gene 3569] {aka BSF-2, BSF2, CDF, HGF, HSF, IFN-beta-2}
- **Diseases:** lameness (MESH:D007794), fractures (MESH:D050723), pain (MESH:D010146), bone tumor (MESH:D001859), Respiratory Diseases (MESH:D012140), loss of vision (MESH:D014786), corneal defects (MESH:D003316), keratoconjunctivitis (MESH:D007637), pancreatic cancer (MESH:D010190), skin injuries (MESH:D000069836), POI (MESH:D016649), mPDAC (MESH:D021441), Traumatic (MESH:D014947), degenerative joint disorder (MESH:D019636), diseases (MESH:D004194), OS (MESH:D012516), liver disease (MESH:D008107), muscle damage (MESH:D009133), Inflammatory (MESH:D007249), DMGs (MESH:D005910), fibrosis (MESH:D005355), TAA (MESH:D017545), Metastatic (MESH:D000092182), hepatic fibrosis (MESH:D008103), pseudoarthrosis (MESH:D011542), MRSA (MESH:D060467), Cancer (MESH:D009369), PMF (MESH:C537404), mesenchymal tumor (MESH:C535700), MAT (MESH:C535434), hyperemia (MESH:D006940), corneal opacity (MESH:D003318), Autoimmune and Allergic Diseases (MESH:D001327), hypoxic (MESH:D002534), mastitis (MESH:D008413), CM (MESH:D010033), cartilage deterioration (MESH:D002357), hypoxia (MESH:D000860), UAP (MESH:D005599), Fat (MESH:D004620), radio-ulnar fracture (MESH:C536268), arthritic (MESH:D015535), OA (MESH:D010003), PCOS (MESH:D011085), Blood Diseases (MESH:D006402), open fracture (MESH:D005597), Liver metastases (MESH:D009362), GIST (MESH:D046152), hip dysplasia (MESH:D006617), bone defects (MESH:D001847), bronchopulmonary dysplasia (MESH:D001997), elbow or knee OA (MESH:D020370), cytotoxic (MESH:D064420), joint effusion (MESH:D000080324), infected fractures (MESH:D007239), abortion (MESH:D000026), mesothelioma (MESH:D008654), impaired muscle function (MESH:D009135), Uterine diseases (MESH:D014591), inflammatory cytokines (MESH:D000080424)
- **Chemicals:** chitosan (MESH:D048271), PS (MESH:D010758), Histamine (MESH:D006632), NaCl (MESH:D012965), OPs (MESH:D009842), PM (MESH:C030090), triglyceride (MESH:D014280), Graphene oxide (MESH:C000628730), PTX (MESH:D017239), calcium gluconate (MESH:D002125), polyethylene glycol (MESH:D011092), N (MESH:D009584), calcium fluoride (MESH:D002124), CHAPS (MESH:C028213), PDS (MESH:D010165), water (MESH:D014867), methicillin (MESH:D008712), barium titanate (MESH:C024547), nitric oxide (MESH:D009569), glycemia (MESH:D001786), HA (MESH:D006820), alphaMEM (MESH:C420642), copper (MESH:D003300), SDS (MESH:D012967), ascorbic acid (MESH:D001205), Fura-2 (MESH:D016257), silica (MESH:D012822), DOXO (MESH:D004317), GAG (MESH:D006025), potassium (MESH:D011188), glycerol (MESH:D005990), RGD (MESH:C047981), hematoxylin (MESH:D006416), Hyp (MESH:D006909), 2-8CELLsius cryomedia (-), TAA (MESH:D013853), H&E (MESH:D006371), PCL (MESH:C016240), fatty acid (MESH:D005227), MTT (MESH:C070243), HOS (MESH:D006695), DHEA (MESH:D003687), LPS (MESH:D008070), PLA (MESH:C033616), lipid (MESH:D008055), TCPS (MESH:C049563), CMs (MESH:D003476), ATP (MESH:D000255), mannitol (MESH:D008353), polystyrene (MESH:D011137), steroid (MESH:D013256), NP (MESH:D009405), DMSO (MESH:D004121), barium (MESH:D001464), calcium (MESH:D002118), ROS (MESH:D017382), calcimycin (MESH:D000001)
- **Species:** Escherichia coli (E. coli, species) [taxon 562], Canis lupus familiaris (dog, subspecies) [taxon 9615], Mus musculus (house mouse, species) [taxon 10090], Human immunodeficiency virus 1 (no rank) [taxon 11676], Homo sapiens (human, species) [taxon 9606], Rattus norvegicus (brown rat, species) [taxon 10116], Staphylococcus aureus (species) [taxon 1280], Bacteria Latreille et al. 1825 (Bacteria stick insect, genus) [taxon 629395], Bos taurus (bovine, species) [taxon 9913], Equus caballus (domestic horse, species) [taxon 9796], Streptococcus agalactiae (species) [taxon 1311]
- **Cell lines:** MAT — Homo sapiens (Human), Childhood T lymphoblastic lymphoma, Cancer cell line (CVCL_RL79), BxPC-3 — Homo sapiens (Human), Pancreatic ductal adenocarcinoma, Cancer cell line (CVCL_0186), HLSC — Homo sapiens (Human), Somatic stem cell (CVCL_AS77), L929 — Mus musculus (Mouse), Spontaneously immortalized cell line (CVCL_AR58), MDBK — Bos taurus (Bovine), Spontaneously immortalized cell line (CVCL_0421), C57BL/6N — Mus musculus (Mouse), Embryonic stem cell (CVCL_2H81), HOS — Homo sapiens (Human), Osteosarcoma, Cancer cell line (CVCL_0312), MG63 — Homo sapiens (Human), Osteosarcoma, Cancer cell line (CVCL_0426), MCF7 — Homo sapiens (Human), Invasive breast carcinoma of no special type, Cancer cell line (CVCL_0031), NCI H2052 — Homo sapiens (Human), Pleural sarcomatoid mesothelioma, Cancer cell line (CVCL_1518), P3S3 — Drosophila melanogaster (Fruit fly), Spontaneously immortalized cell line (CVCL_Z233), DH82 — Canis lupus familiaris (Dog), Canine histiocytic sarcoma, Cancer cell line (CVCL_2018), SJSA — Homo sapiens (Human), Osteosarcoma, Cancer cell line (CVCL_1697), fibroblasts — Mus musculus (Mouse), Spontaneously immortalized cell line (CVCL_0594), C — Mus musculus (Mouse), Finite cell line (CVCL_S361), HMEC — Homo sapiens (Human), Transformed cell line (CVCL_0307), K8484 — Mus musculus (Mouse), Mouse pancreatic neoplasm, Cancer cell line (CVCL_XD12), WJ — Homo sapiens (Human), Glioblastoma, Cancer cell line (CVCL_W352)

## Full text

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Source: https://tomesphere.com/paper/PMC12540261