# Treatment of Bipolar Disorder by a Community Mental Health Service in a Rural Catchment Area in Greece: Treatment Engagement and Outcomes

**Authors:** Vaios Peritogiannis, Dimitra Moschou, Panagiota Gioti, Michailia Chlachla, Georgia Xiromerisiou

PMC · DOI: 10.62641/aep.v53i5.1900 · Actas Españolas de Psiquiatría · 2025-10-05

## TL;DR

This study examines how a mobile mental health unit in rural Greece treats bipolar disorder, focusing on treatment engagement and hospitalization outcomes.

## Contribution

The study provides insights into treatment engagement and outcomes for bipolar disorder in a rural Greek setting using mobile mental health units.

## Key findings

- An 81.3% treatment engagement rate was observed within one year, dropping to 52.1% at the study endpoint.
- Treatment-engaged patients showed a significant reduction in total and voluntary hospitalizations.
- Length of hospital stay was significantly reduced after treatment engagement.

## Abstract

The course of bipolar disorder (BD) may be disabling on several occasions, whereas management of BD may be challenging due to poor treatment adherence and high service-disengagement rates. Such challenges in the treatment of BD may be even more relevant in rural settings. In rural Greece, treatment of mental disorders may be almost exclusively delivered by the interdisciplinary Mobile Mental Health Units (MMHUs). The objective of the study was to explore treatment of BD by a MMHU in a rural setting in Greece.

All medical records of BD patients that have been examined by the MMHU of Ioannina and Thesprotia (MMHU I-T) over a 17-year period (2007–2023) were assessed retrospectively. The studied outcomes were 1-year treatment engagement; treatment engagement at the study endpoint; and changes in hospitalizations and length of hospital stay in treatment-engaged patients.

From a total of 62 examined patients, data was analyzed for 48 cases. The 1-year engagement rate was 81.3%, which dropped to 52.1% at the study endpoint, with a mean follow-up of 7.2 ± 4.0 years. Treatment-engaged patients were more likely to receive a mood stabilizer than disengaged patients. In treatment-engaged patients a significant reduction in total and voluntary hospitalizations was observed, whereas involuntary admissions remained unchanged. Length of hospital stay was significantly reduced after treatment engagement.

The results of the study are in line with previous research in Greek rural settings. The impact of the care by MMHUs on involuntary admissions in BD patients warrants further study. Future research should be multi-centered, with prospective design, and should address additional outcomes.

## Linked entities

- **Diseases:** bipolar disorder (MONDO:0004985)

## Full-text entities

- **Diseases:** mental disorders (MESH:D001523), BD (MESH:D001714)
- **Chemicals:** MMHU (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

34 references — full list in the complete paper: https://tomesphere.com/paper/PMC12538611/full.md

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Source: https://tomesphere.com/paper/PMC12538611