# Critical Overview of Screening Tools for Detecting Bipolar Disorders

**Authors:** Micaela Dines, Carolina Hernandorena, Veronica Grasso, Gustavo Vazquez

PMC · DOI: 10.62641/aep.v53i5.1924 · Actas Españolas de Psiquiatría · 2025-10-05

## TL;DR

This paper reviews four screening tools for bipolar disorders, comparing their strengths and weaknesses to help healthcare professionals choose the best one for different situations.

## Contribution

The paper provides a critical comparative analysis of four bipolar disorder screening tools, highlighting their specific diagnostic performance and clinical utility.

## Key findings

- The MDQ has high specificity (0.90) for BD but is more sensitive to bipolar I than bipolar II.
- The HCL-32 is effective for distinguishing BD from unipolar depression but cannot differentiate between BD I and BD II.
- Using multiple screening tools together improves diagnostic accuracy for bipolar disorders.

## Abstract

This overview aims to explore the key screening tools for detecting bipolar disorders (BDs): the Mood Disorder Questionnaire (MDQ), Bipolar Spectrum Diagnostic Scale (BSDS), Hypomania Checklist (HCL-32), and Rapid Mood Screener (RMS), while offering guidance to healthcare professionals in selecting the most appropriate tool for each clinical scenario. The MDQ is widely utilized due to its high specificity (0.90) for identifying Bipolar Disorder (BD) in psychiatric consultations, although it is more sensitive to bipolar I than bipolar II. The BSDS, designed to encompass a wider range of bipolar spectrum symptoms, exhibits a sensitivity of 0.70 and specificity of 0.89, which makes it a complementary tool to the MDQ. The HCL-32 concentrates on detecting hypomanic traits in Major Depressive Disorder (MDD) patients, showing good sensitivity (80%) but lower specificity (51%). It is particularly effective for distinguishing BD from unipolar depression, although it cannot differentiate between Bipolar Disorder type I (BDI) and Bipolar Disorder type II (BDII). The RMS is a newer tool that quickly screens for manic symptoms and risk factors, boasting a sensitivity of 0.88 and a specificity of 0.80. Together, these screening instruments facilitate the early identification of BDs, though positive results should always be followed by a thorough clinical evaluation. Employing multiple tools simultaneously can improve diagnostic accuracy and more effectively capture the diverse presentations of BDs.

## Linked entities

- **Diseases:** Bipolar Disorder (MONDO:0004985), Major Depressive Disorder (MONDO:0002009)

## Full-text entities

- **Diseases:** MDD (MESH:D003865), Mood (MESH:D019964), Hypomania (MESH:D000087122), unipolar depression (MESH:D003866), BDI (MESH:D001714), psychiatric (MESH:D001523)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

24 references — full list in the complete paper: https://tomesphere.com/paper/PMC12538600/full.md

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Source: https://tomesphere.com/paper/PMC12538600