# Stewarding waste and antimicrobials: an assessment of chorioamnionitis regimens

## TL;DR

This paper compares antibiotic regimens for chorioamnionitis, highlighting that some treatments produce more plastic waste than others.

## Contribution

The study introduces a novel perspective on antibiotic stewardship by evaluating treatment regimens based on their plastic waste generation.

## Key findings

- Ampicillin with gentamicin ± clindamycin generates more plastic waste compared to other regimens.
- Vancomycin with gentamicin also produces higher plastic waste than alternatives like cefoxitin or ertapenem.

## Abstract

Stewardship is not only about appropriate antibiotic prescribing, but also improving the utilization of resources. While multiple treatment regimens are endorsed for chorioamnionitis, some produce significantly more plastic waste than others. Ampicillin with gentamicin ± clindamycin, and vancomycin with gentamicin both create more plastic waste compared to regimens like cefoxitin, piperacillin/tazobactam, or ertapenem.