# Incidence of local complications following implementation of alcoholic chlorhexidine for peripheral venous catheter site disinfection

**Authors:** Ventsislava Berg, Martin Nufer, Michaela Gligor, Christina Orasch, Rami Sommerstein

PMC · DOI: 10.1017/ash.2025.10170 · Antimicrobial Stewardship & Healthcare Epidemiology : ASHE · 2025-10-14

## TL;DR

Using alcoholic chlorhexidine for catheter site disinfection did not significantly change local skin complication rates in real-world practice.

## Contribution

Real-world validation of chlorhexidine's infection prevention without increasing skin complications.

## Key findings

- CHG disinfection did not increase local skin complications.
- Implementation of CHG showed no major change in complication incidence.
- Real-world application confirmed controlled study benefits without new risks.

## Abstract

A previous controlled study showed advantages of 2% Chlorhexidine Gluconate-Alcohol (CHG) over Povidone-Iodine-Alcohol in preventing infections after peripheral venous catheter placement. We applied these findings in a real-world before/after healthcare intervention and found that introduction of CHG disinfection was not associated with a major change of incidence in local skin complications.

## Full-text entities

- **Diseases:** infections (MESH:D007239), skin complications (MESH:D012871)
- **Chemicals:** CHG (-), chlorhexidine (MESH:D002710)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12538344/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12538344/full.md

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Source: https://tomesphere.com/paper/PMC12538344