# Potential Effect of Intravesical Platelet‐Rich Plasma Injection on Urinary Retention: A Case Report

**Authors:** Kangji Liao, Qiguang Li, Xianlin Yi

PMC · DOI: 10.1002/ccr3.71278 · Clinical Case Reports · 2025-10-21

## TL;DR

A patient with urinary retention after cervical cancer treatment showed improvement with intravesical platelet-rich plasma injections.

## Contribution

Intravesical platelet-rich plasma is proposed as a potential treatment for urinary retention after pelvic tumor surgery.

## Key findings

- Platelet-rich plasma injections improved bladder emptying and mucosal healing in a patient with radiation cystitis.
- The treatment may offer a new approach for managing post-surgical urinary retention.
- Controlled clinical trials are needed to validate these findings.

## Abstract

Pelvic autonomic nerve injury during radical treatment of cervical cancer and postoperative radiotherapy leads to bladder dysfunction and urinary retention. At present, there is no specific treatment. We report a 51‐year‐old patient with cervical adenocarcinoma who developed acute radiation cystitis and urinary retention 2 months after radiotherapy. We used three courses of intravesical injection of platelet‐rich plasma, which improved the patient's bladder emptying function and restored the bladder mucosa. We believe that intravesical injection of platelet‐rich plasma can not only be used to treat acute radiation cystitis, but also be a potential treatment for urinary retention after pelvic tumor surgery. However, further controlled clinical trials are needed to confirm.

## Linked entities

- **Diseases:** cervical cancer (MONDO:0002974)

## Full-text entities

- **Diseases:** pelvic tumor (MESH:D010386), cervical adenocarcinoma (MESH:D000230), radiation cystitis (MESH:D011832), Urinary Retention (MESH:D016055), cervical cancer (MESH:D002583), Pelvic autonomic nerve injury (MESH:D000080902), bladder dysfunction (MESH:D001745)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12538232/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12538232/full.md

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Source: https://tomesphere.com/paper/PMC12538232