# A Novel Hypomorphic STAT3 Gene Variant in a 7-year-old Male with Hyper-IgE Syndrome

**Authors:** Tomoko Higashigawa, Yukiko Ikeyama, Kosuke Ashihara, Takaki Asano, Satoshi Okada, Yuki Miwa, Katsumi Sugiura, Hidenori Ohnishi

PMC · DOI: 10.1007/s10875-025-01942-7 · Journal of Clinical Immunology · 2025-10-20

## Full-text entities

- **Genes:** STAT3 (signal transducer and activator of transcription 3) [NCBI Gene 6774] {aka ADMIO, ADMIO1, APRF, HIES}
- **Diseases:** Hyper-IgE Syndrome (MESH:D007589)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12537600/full.md

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12537600/full.md

## References

1 references — full list in the complete paper: https://tomesphere.com/paper/PMC12537600/full.md

---
Source: https://tomesphere.com/paper/PMC12537600