# Hepatogastric Fistula as a Rare Complication of Pyogenic Liver Abscess: A Case Report

**Authors:** Mohammad Kazem Amirbeigy, Amir Pasha Amel Shahbaz, Zahra Sekandari, Shahab Sheikhalishahi

PMC · DOI: 10.1002/ccr3.71331 · Clinical Case Reports · 2025-10-20

## TL;DR

A rare case of a liver abscess complication leading to a fistula between the liver and stomach is reported in an 18-year-old male.

## Contribution

This case report presents a rare hepatogastric fistula as a complication of pyogenic liver abscess in a young patient.

## Key findings

- Triphasic CT and endoscopy confirmed a fistula between the liver and gastric antrum.
- Staphylococcus aureus was identified as the causative organism and treated with targeted antibiotics.
- Laparoscopic cholecystectomy revealed no cholecystoenteric fistula, and the patient recovered well.

## Abstract

Hepatogastric fistula is a rare complication of pyogenic liver abscess. We report an 18‐year‐old male with 3 weeks of fever, melena, and epigastric discomfort. Ultrasound showed a contracted gallbladder with wall thickening and sludge without cholelithiasis. Triphasic CT demonstrated a solid–cystic collection in hepatic segments IV and V abutting the gastric antrum, compatible with a fine communication. Esophagogastroduodenoscopy revealed a 3 mm antral mucosal orifice with purulent drainage. Smear showed neutrophil‐predominant exudate and Gram‐positive cocci; culture yielded 
Staphylococcus aureus
 susceptible to ciprofloxacin and clindamycin. Therapy was narrowed to ciprofloxacin 400 mg twice daily and clindamycin 600 mg three times daily. A 14‐day 
Helicobacter pylori
 eradication regimen was completed. Subsequently, laparoscopic cholecystectomy was performed. Intraoperatively the gallbladder was contracted with an inflamed but intact wall containing sludge; Calot's triangle was edematous yet the critical view of safety was obtained, and no cholecystoenteric fistula was identified. No drainable hepatic collection was present, consistent with decompression through the antral orifice. Opening the specimen demonstrated microlithiasis. Recovery was uneventful, and the patient remained with normal laboratory indices at 3 months. This case highlights the complementary roles of cross‐sectional imaging and endoscopy and supports individualized management in young patients with biliary‐source liver abscess.

## Linked entities

- **Chemicals:** ciprofloxacin (PubChem CID 2764), clindamycin (PubChem CID 446598)

## Full-text entities

- **Diseases:** microlithiasis (MESH:C566478), liver abscess (MESH:D008100), Hepatogastric Fistula (MESH:D005402), cholelithiasis (MESH:D002769), Pyogenic Liver Abscess (MESH:D046290), fever (MESH:D005334), melena (MESH:D008551)
- **Chemicals:** ciprofloxacin (MESH:D002939), clindamycin (MESH:D002981)
- **Species:** Homo sapiens (human, species) [taxon 9606], Staphylococcus aureus (species) [taxon 1280], Helicobacter pylori (species) [taxon 210]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12537542/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12537542/full.md

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Source: https://tomesphere.com/paper/PMC12537542