# PRF‐Assisted Regenerative Endodontic Retreatment of an Immature Tooth: A 4‐Year Follow‐Up

**Authors:** Pegah Sarraf, Bardia Goldani, Mehrfam Khoshkhounejad, Fatemeh Hamidzadeh

PMC · DOI: 10.1002/ccr3.71306 · Clinical Case Reports · 2025-10-20

## TL;DR

This paper reports a successful 4-year outcome of regenerative endodontic retreatment in an immature tooth with persistent infection.

## Contribution

The study demonstrates long-term success of nonsurgical regenerative retreatment in a complex immature tooth case.

## Key findings

- Regenerative endodontic retreatment led to long-term healing in an immature tooth.
- Proper case selection and disinfection are critical for successful outcomes.
- Stem cell viability preservation supports continued root development.

## Abstract

Regenerative endodontic retreatment can be a viable nonsurgical option for previously treated immature teeth with persistent periapical pathology. With proper case selection, meticulous disinfection, and preservation of stem cell viability, long‐term healing and continued root development can be achieved even in complex retreatment cases.

## Full-text entities

- **Diseases:** periapical pathology (MESH:D010483)

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12537540/full.md

## References

30 references — full list in the complete paper: https://tomesphere.com/paper/PMC12537540/full.md

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Source: https://tomesphere.com/paper/PMC12537540