# Population-based analysis of the association between composite dietary antioxidant index and pediatric obesity

## TL;DR

This study finds that higher antioxidant intake in children's diets is linked to lower obesity rates, based on a large U.S. health survey.

## Contribution

This is the first study to examine the association between the composite dietary antioxidant index and pediatric obesity.

## Key findings

- Higher CDAI scores were significantly associated with lower BMI and WHtR in children and adolescents.
- A one-unit increase in CDAI reduced obesity odds by 1.9% based on WHtR.
- The relationship between CDAI and obesity metrics varied across subgroups.

## Abstract

Pediatric obesity is an increasingly serious global problem. Although much attention has been paid to the role of nutrition in pediatric obesity, no prior study has examined the association between the composite dietary antioxidant index (CDAI), the main measure of an antioxidative diet, and pediatric obesity, and this research aims to investigate this relationship.

Using the National Health and Nutrition Examination Survey (NHANES) for the period 2009–2018, we examined the relationship between CDAI and pediatric obesity: body mass index (BMI) and waist-to-height ratio (WHtR) using multivariate linear regression models and smoothing fit curves. Furthermore, subgroup analyses were conducted to observe differences in these associations across various stratifying factors.

Our study encompassed 10,019 participants aged 6–18 years with complete data. There was a significant negative correlation between CDAI and BMI (β = −0.04, 95% CI: −0.09, −0.00, p = 0.0367) and WHtR (β = −0.08, 95% CI: −0.15, −0.02, p = 0.0089). Additionally, a one-unit increase in CDAI was linked to a 1.9% decrease in the odds of obesity as defined by WHtR (OR = 0.98, 95% CI: 0.96, 1.00, p = 0.0342). Notably, the negative associations between CDAI and both BMI and WHtR varied across subgroups.

Our findings reveal a linear negative relationship between CDAI and both BMI and WHtR among American children and adolescents, offering novel insights into the potential protective role of antioxidant-rich diets against pediatric obesity.