# Preprocedural computed tomography angiography-guided transcatheter arterial embolization for managing esophageal cancer bleeding: a case series study

**Authors:** Xue-Jiao Yang, Yong-Juan Wu, Jing-Zhong Wang, Yu-Lan Zheng, Guang-Yuan Cheng, Yun-Hua Cui, Xiao-Qi Li

PMC · DOI: 10.3389/fonc.2025.1598271 · Frontiers in Oncology · 2025-10-07

## TL;DR

This study shows that CTA-guided TAE is effective for stopping bleeding in esophageal cancer patients, with high success rates and manageable side effects.

## Contribution

The study introduces preprocedural CTA guidance as a novel approach to improve TAE outcomes for esophageal cancer bleeding.

## Key findings

- Seven out of eight patients achieved both technical and clinical success with CTA-guided TAE.
- Five patients experienced recurrent bleeding, with four dying and one successfully treated with a second TAE.
- CTA-guided TAE was associated with mild and manageable complications in most patients.

## Abstract

While endoscopy is the first-line treatment for non-variceal upper gastrointestinal hemorrhage, its role in managing upper gastrointestinal tumor bleeding is limited. This study aims to evaluate the effect of computed tomography angiography (CTA)-guided transcatheter arterial embolization (TAE) in achieving hemostasis for esophageal cancer bleeding.

A retrospective case series was conducted at our hospital, involving eight patients who underwent preprocedural CTA-guided TAE for esophageal cancer bleeding between August 2023 and August 2024.

Of the eight patients (seven males, mean age 67 ± 12.9 years) who underwent CTA-guided TAE for esophageal cancer bleeding, seven achieved both technical and clinical success. One patient failed to achieve embolization due to missed identification of a pseudoaneurysm in the superior thyroid artery, resulting in death from hemorrhage. Two patients experienced mild chest or neck discomfort, which resolved with conservative management. During follow-up, five patients experienced recurrent hemorrhage, with four dying and one successfully treated with a second TAE. One of the remaining two patients died from disease progression, and the other remained recurrence-free for 270 days.

CTA-guided TAE demonstrates high technical and clinical success rates for achieving hemostasis in esophageal cancer bleeding with mild and manageable complications.

## Linked entities

- **Diseases:** esophageal cancer (MONDO:0007576)

## Full-text entities

- **Diseases:** upper gastrointestinal hemorrhage (MESH:D006471), death (MESH:D003643), esophageal cancer bleeding (MESH:D004938), hemorrhage (MESH:D006470), pseudoaneurysm (MESH:D017541)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12537362/full.md

## References

28 references — full list in the complete paper: https://tomesphere.com/paper/PMC12537362/full.md

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Source: https://tomesphere.com/paper/PMC12537362