# Factors influencing type 2 diabetes in adults: a cross-sectional study

**Authors:** Yan Zou, Li-chun Huang, Meng-jie He, Dan Han, Dan-ting Su, Pei-wei Xu, Rong-hua Zhang

PMC · DOI: 10.3389/fpubh.2025.1662519 · Frontiers in Public Health · 2025-10-07

## TL;DR

This study identifies age, obesity, hypertension, and high triglycerides as risk factors for type 2 diabetes in adults in Zhejiang Province.

## Contribution

The study provides new insights into modifiable risk factors for T2DM in a Chinese adult population.

## Key findings

- Prevalence rates of T2DM and prediabetes were 5.5% and 5.8%, respectively.
- Overweight, obesity, hypertension, and elevated triglycerides significantly increased diabetes risk.
- Targeted interventions are needed to manage these risk factors for diabetes prevention.

## Abstract

The aim of this study was to explore the factors influencing type 2 diabetes mellitus (T2DM) among adults in Zhejiang Province.

A stratified cluster sampling technique was employed, and adults without known diabetes were included in the analysis. Food consumption was assessed using three consecutive days of 24-h dietary recall. Blood samples were collected to measure fasting blood glucose (FBG), blood lipids [total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), 25-(OH)D vitamin D (VD), and vitamin A (VA). Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were also measured. Ordinal regression was used to explore factors influencing T2DM.

The analysis included a total of 5,804 adults. The prevalence rates of T2DM and prediabetes were 5.5 and 5.8%, respectively. Significant differences were observed in age, sex, nutritional status, hypertension, and blood lipid levels among adults with normal fasting blood glucose, prediabetes, and T2DM (p < 0.05). Adults aged 55 years and above, those who were overweight or obese, those with hypertension, and those with higher TG levels had a greater risk of developing diabetes (p < 0.05).

This study revealed that adults aged 55 years and above, those who are overweight or obese, those with hypertension, and those with higher TG levels have a greater risk of developing diabetes. These findings underscore the need for targeted interventions to manage these risk factors in the prevention and management of T2DM.

## Linked entities

- **Diseases:** prediabetes (MONDO:0006920)

## Full-text entities

- **Diseases:** diabetes (MESH:D003920), T2DM (MESH:D003924), overweight (MESH:D050177), obese (MESH:D009765), prediabetes (MESH:D011236), hypertension (MESH:D006973)
- **Chemicals:** 25-(OH)D vitamin D (-), VD (MESH:D014807), glucose (MESH:D005947), cholesterol (MESH:D002784), VA (MESH:D014801), TG (MESH:D014280), lipid (MESH:D008055)

## Full text

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## References

35 references — full list in the complete paper: https://tomesphere.com/paper/PMC12537354/full.md

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Source: https://tomesphere.com/paper/PMC12537354