# The value of metabolic surgery for patients with obesity and type 2 diabetes in Romania

**Authors:** Gábor Kovács, László Lorenzovici, Cătălina Poiană, Adriana Florinela Catoi, Ciprian Duta, Daniel Vasile Timofte, Marius Florin Coros, Sándor Siménfalvi, Szabolcs Farkas-Ráduly, Tamás Török, Andrea Timea Jakab, Andrea Kacsó, László Nagy, László Imre, Dávid Nagy, Catalin Andu Copaescu, Bogdan Cristian Pana

PMC · DOI: 10.3389/fnut.2025.1624280 · Frontiers in Nutrition · 2025-10-07

## TL;DR

Metabolic surgery is shown to be cost-effective and beneficial for obese patients with type 2 diabetes in Romania, potentially warranting inclusion in public healthcare.

## Contribution

This study evaluates the cost-effectiveness of metabolic surgery in Romania using a tailored Central European model adapted to local data.

## Key findings

- Metabolic surgery was found to be cost-saving and improve health outcomes across all BMI categories.
- The surgery significantly reduced healthcare costs and diabetes-related complications.
- The intervention remained cost-effective even under conservative assumptions.

## Abstract

Metabolic surgery is a well-established intervention for managing severe obesity and type 2 diabetes, offering significant long-term health benefits. In Europe, procedures such as sleeve gastrectomy and Roux-en-Y gastric bypass have been shown to improve glycemic control, reduce obesity-related comorbidities, and enhance quality of life. Given the high prevalence of obesity in Romania, evaluating the cost-effectiveness of these surgical interventions is crucial for potential public funding inclusion.

We adapted a Central European type 2 diabetes—metabolic surgery cost-utility model using Romanian epidemiological and healthcare cost data to assess the cost-effectiveness of weight-loss surgery. The model incorporated three Body Mass Index strata (30–34.9, 35–39.9, ≥40 kg/m2) and tracked outcomes over a lifetime horizon. Cost and quality-adjusted life years were evaluated for sleeve gastrectomy and Roux-en-Y gastric bypass using two costing methodologies: Diagnosis-Related Group-based reimbursement and micro-costing analysis. Scenario analyses, including threshold analysis, were conducted to validate model robustness.

Obesity surgery was found to be a dominant strategy, yielding both cost savings and improved health outcomes across all Body Mass Index categories. The intervention led to increased life expectancy, reduced diabetes-related complications, and a significant reduction in healthcare costs. Even under conservative cost assumptions, the surgery remained cost-effective, with an Incremental Cost-Effectiveness Ratio (ICER) well within European funding thresholds.

The results support the inclusion of metabolic surgery in Romania’s public healthcare system. Expanding access could reduce long-term healthcare expenditures while improving the quality of life for individuals with obesity and type 2 diabetes.

## Linked entities

- **Diseases:** type 2 diabetes (MONDO:0005148), obesity (MONDO:0011122)

## Full-text entities

- **Diseases:** weight-loss (MESH:D015431), Obesity (MESH:D009765), diabetes (MESH:D003920), type 2 diabetes (MESH:D003924)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12537302/full.md

## References

60 references — full list in the complete paper: https://tomesphere.com/paper/PMC12537302/full.md

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Source: https://tomesphere.com/paper/PMC12537302