# Sellar–suprasellar pituitary lymphoma mimicking pituitary adenoma: a case report with literature review

## TL;DR

A rare case of sellar–suprasellar pituitary lymphoma was mistaken for a pituitary adenoma, highlighting the need for accurate diagnosis and multidisciplinary treatment.

## Contribution

This case report adds to the limited literature on sellar–suprasellar lymphoma and emphasizes its diagnostic and therapeutic challenges.

## Key findings

- The patient was initially diagnosed with a pituitary macroadenoma but was later found to have diffuse large B-cell lymphoma.
- Treatment with chemotherapy and radiotherapy reduced the tumor mass and improved symptoms.
- The case highlights the importance of considering SSL in unusual sellar masses.

## Abstract

Sellar–suprasellar lymphoma (SSL) is an extremely rare tumor, constituting fewer than 1%. It is a variant of primary central nervous system lymphoma. SSL is usually seen in people around 60 years of age, exhibiting a slight female predominance. Diffuse large B-cell lymphoma represents the most predominant subtype. We report a 57-year-old female with a 9-month history of worsening severe left-sided headaches involving the left eye, associated with nausea, vomiting, blurred vision, and significant unintentional weight loss. Initial imaging revealed a pituitary tumor, and she was diagnosed with a pituitary macroadenoma. She underwent endoscopic trans-sphenoidal debulking. Histopathological examination confirmed a high-grade diffuse large B-cell lymphoma. She was treated with chemotherapy and radiotherapy which reduced the mass and improved her symptoms. Our case underscores the importance of considering SSL, particularly in patients with unusual sellar masses. Effective treatment needs a multidisciplinary approach, integrating radiotherapy and endocrine support when demanded.