# An Aggressive Cerebral Cavernous Malformation Presenting With Hemorrhage: A Case Report

**Authors:** Yuki Hayashi, Shusaku Matsuo, Ryusei Seo, Takumi Kitamura, Takeshi Torigai

PMC · DOI: 10.7759/cureus.92776 · Cureus · 2025-09-20

## TL;DR

A 23-year-old woman with a rare brain vascular malformation experienced aggressive bleeding, leading to surgical removal and recovery.

## Contribution

This case report highlights the aggressive nature of a cerebral cavernous malformation and the effectiveness of surgical intervention.

## Key findings

- The lesion increased in size from 33.8 mm to 46.8 mm within a month.
- Surgical resection was performed to prevent further neurological deterioration.
- The patient recovered without neurological deficits post-surgery.

## Abstract

Cerebral cavernous malformations (CCMs) are rare vascular malformations that are typically not visualized on cerebral angiography and are often discovered incidentally on brain MRI. However, it may also present symptomatically with seizures or intracerebral hemorrhage. We report the case of a 23-year-old woman in whom a hemorrhagic CCM located in the right temporal lobe was identified following a 10-day history of headache accompanied by nausea and vomiting. Initial management involved conservative observation. However, within approximately one month, the lesion demonstrated two episodes of asymptomatic rebleeding and an increase in size from 33.8 mm to 46.8 mm in maximum diameter, indicating highly aggressive behavior. Given the potential risk of neurological deterioration or even fatal outcomes from further hemorrhages, surgical resection was performed. The patient was discharged without any neurological deficits and is scheduled for follow-up with outpatient MRI surveillance.

## Linked entities

- **Diseases:** cerebral cavernous malformations (MONDO:0020724), intracerebral hemorrhage (MONDO:0013792)

## Full-text entities

- **Diseases:** seizures (MESH:D012640), CCMs (MESH:D020786), neurological deficits (MESH:D009461), Hemorrhage (MESH:D006470), neurological deterioration (MESH:D009422), nausea (MESH:D009325), vascular malformations (MESH:D054079), headache (MESH:D006261), vomiting (MESH:D014839), intracerebral hemorrhage (MESH:D002543)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12536668/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12536668/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12536668/full.md

---
Source: https://tomesphere.com/paper/PMC12536668