# Effect of an exosuit on kinematics in individuals with incomplete spinal cord injury

**Authors:** Lara Visch, Brenda E. Groen, Alexander C. H. Geurts, Ilse J. W. van Nes, Noël L. W. Keijsers

PMC · DOI: 10.1177/20556683251375068 · Journal of Rehabilitation and Assistive Technologies Engineering · 2025-10-16

## TL;DR

This study compares how an anti-gravity exosuit affects walking in people with incomplete spinal cord injury, finding limited gait improvements compared to regular walking and a body weight support system.

## Contribution

The novel contribution is evaluating an anti-gravity exosuit's impact on gait kinematics in individuals with incomplete spinal cord injury using direct comparisons to regular walking and BWS.

## Key findings

- Exosuit increased hip extension compared to regular walking but not compared to BWS.
- Knee flexion was reduced in both exosuit vs. regular and exosuit vs. BWS comparisons.
- Most secondary gait measures showed no improvement with exosuit compared to regular walking.

## Abstract

Anti-gravity exosuits supporting hip and knee extension have emerged for overground training. This study investigated their effect on kinematics in individuals with incomplete spinal cord injury (iSCI) compared to regular walking and to walking with an overground BWS system.

Fourteen individuals with iSCI were tested during overground walking in three conditions: regular, exosuit, and BWS. Kinematics were assessed using the Xsens MVN motion capture system.

Maximum hip extension was larger for exosuit compared to regular walking (Δ4.7°, 95% CI [1.4, 7.9]), but was not different compared to BWS. Mean knee flexion was smaller for exosuit compared to regular walking (Δ−1.7°, 95% CI [−3.0, −0.4]) and compared to BWS (Δ−3.5°, 95% CI [−5.4, -1.6]). Most secondary outcome measures (e.g. walking speed, stride length, step width, ML COM excursion) showed no differences between exosuit and regular walking. Comparing exosuit to BWS, most secondary outcome measures (e.g., walking speed, stride length, stride time, trunk inclination) favored BWS.

An anti-gravity exosuit resulted in increased hip and knee extension, but did not translate into other gait improvements. Given the more favorable outcomes of the BWS system compared to the exosuit, exosuit design improvements are needed to be effectively implemented in gait rehabilitation after iSCI.

## Linked entities

- **Diseases:** spinal cord injury (MONDO:0043797)

## Full-text entities

- **Diseases:** iSCI (MESH:D013119)

## Full text

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## Figures

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## References

31 references — full list in the complete paper: https://tomesphere.com/paper/PMC12536207/full.md

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Source: https://tomesphere.com/paper/PMC12536207