# Multisystem inflammatory syndrome in children associated with COVID-19: a case report and literature review

## TL;DR

This paper reports a case of a child with severe multisystem inflammatory syndrome linked to COVID-19, emphasizing the need for early diagnosis and treatment.

## Contribution

The novelty lies in highlighting MIS-C misdiagnosis as acute gastroenteritis and the importance of rapid escalation of care.

## Key findings

- The child showed worsening symptoms and abnormal lab results despite antibiotic treatment.
- IVIG and additional therapies like inotropes were required due to myocarditis.
- Early recognition and treatment of MIS-C can reduce severe outcomes.

## Abstract

Given the rarity of multisystem inflammatory syndrome related to COVID-19 (MIS-C). This case report highlights the high index of suspicion to diagnose MIS-C in a child who presented with symptoms suggestive of acute gastroenteritis. While admitted in the hospital, she deteriorated with worsening of symptoms, clinical decline, deranged laboratory markers, and significant radiological findings, even though on antibiotics. She had acute myocarditis with myocardial dysfunction on echocardiography and raised cardiac enzymes. Intravenous human immunoglobulin (IVIG) was given, but there was additional need for inotrope (norepinephrine) and methylprednisolone albeit the preliminary echocardiogram was normal. Early recognition of MIS-C with rapid escalation of care post IVIG administration is needed to prevent morbidity and mortality.