# Robot-assisted extended thymectomy in juvenile myasthenia gravis: first case performed in Ecuador

**Authors:** Enrique Gagliardo, Luis Aguaguiña Toainga, Janneth Alejandra Pérez Cedeño, Luis Alberto Barrera Delgado, Luis Munoz Andrade

PMC · DOI: 10.1093/jscr/rjaf759 · Journal of Surgical Case Reports · 2025-10-18

## TL;DR

This paper reports the first robot-assisted thymectomy for juvenile myasthenia gravis in Ecuador, showing successful clinical improvement.

## Contribution

The first reported case of robot-assisted extended thymectomy for juvenile myasthenia gravis in Ecuador.

## Key findings

- The surgery was uneventful and resulted in marked clinical improvement.
- There was no recurrence of myasthenic crises during follow-up.
- Advanced surgical techniques can be feasible in low-resource settings.

## Abstract

Myasthenia gravis (MG) is a chronic autoimmune disorder characterized by fatigable muscle weakness, typically caused by antibodies against acetylcholine receptors (AChR) or muscle-specific kinas. While it primarily affects adults, juvenile cases represent a significant minority and often pose greater therapeutic challenges. Extended thymectomy has proven beneficial in AChR-positive MG, reducing symptoms and immunosuppressive needs. Robotic-assisted thymectomy offers enhanced precision with lower morbidity. We report the first such procedure in Ecuador, performed on a 21-year-old woman with recurrent myasthenic crises. The surgery was uneventful, and follow-up showed marked clinical improvement without recurrence, highlighting the feasibility of advanced techniques in low-resource settings.

## Linked entities

- **Diseases:** myasthenia gravis (MONDO:0009688), juvenile myasthenia gravis (MONDO:0018325)

## Full-text entities

- **Diseases:** muscle weakness (MESH:D018908), MG (MESH:D009157), myasthenic crises (MESH:D013224), autoimmune disorder (MESH:D001327)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12535260/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12535260/full.md

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Source: https://tomesphere.com/paper/PMC12535260