# Outcomes Following the Arthroscopic Chondro-Gide Repair of Osteochondral Defects of the Talus

**Authors:** Yousef Al-Khatib, Daniel Haddad, Adesina Adetokunbo, Bennet Aboagye, Karim Hussien, Raghubir Kankate, Radwane Faroug

PMC · DOI: 10.7759/cureus.92621 · Cureus · 2025-09-18

## TL;DR

This study shows that arthroscopic repair using Chondro-Gide improves ankle function and reduces pain in patients with talar osteochondral defects.

## Contribution

The study provides new evidence on the effectiveness of Chondro-Gide for treating talar OCDs, which is under-researched.

## Key findings

- Postoperative OMAS scores improved significantly from 30 to 72.7 (p<0.01).
- VAS scores decreased from 7.85 preoperatively to 2.69 postoperatively (p<0.01).
- Lesion diameter did not significantly correlate with OMAS score improvement (p>0.05).

## Abstract

Background and objective

Osteochondral defects (OCD) of the talus are associated with pain and ankle joint dysfunction. Autologous matrix-induced chondrogenesis (AMIC) is one of the arthroscopic surgical techniques described for the treatment of talar OCD. There is scarce evidence regarding the use of Chondro-Gide or any other synthetic matrix for OCD of the talus. We aimed to investigate patient outcomes following Chongro-Gide repair of talar OCDs, along with the relationship between lesion diameter and patient outcomes.

Methods

A retrospective cross-sectional study was carried out, and patient outcomes were recorded. Olerud-Molander Ankle Score (OMAS) was documented for each patient during clinic follow-ups, as well as visual analogue scores (VAS). Both preoperative and postoperative OMAS and VAS scores were recorded at the 12-week postoperative follow-up. The other factors recorded were as follows: lesion size, site of OCD, postoperative complications, patient age, and gender.

Results

Sixteen patients were identified with isolated talus OCD. The mean preoperative OMFAS was 30 (range: 10-45) while the postoperative OMAS was 72.7 (range: 65-100, p<0.01). The mean VAS score was 7.85 preoperatively compared to 2.69 postoperatively (p<0.01). The average OCD diameter was 8.9 mm (range: 3-14). There was no statistically significant correlation between OCD lesion diameter and improvement in OMAS scores (p>0.05). The most commonly reported complication by patients was postoperative stiffness.

Conclusions

We observed positive outcomes following arthroscopic osteochondral lesion repair using AMIC Chondro-Gide. While there is a paucity of evidence on the use of AMIC to treat talar OCDs, our study adds to the growing evidence endorsing arthroscopic AMIC with Chondro for treating talar OCDs.

## Linked entities

- **Diseases:** osteoarthritis (MONDO:0005178)

## Full-text entities

- **Diseases:** pain (MESH:D010146), OCD (MESH:D010007), stiffness (MESH:C566112), ankle joint dysfunction (MESH:D064386), AMIC (MESH:C536017)
- **Chemicals:** AMIC Chondro-Gide (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12535178/full.md

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Source: https://tomesphere.com/paper/PMC12535178