# A Rare Case of Metastatic Adenoid Cystic Carcinoma in the Liver: A Case Report

**Authors:** Sohaib Khalid, Iram Khan, Urfa Shafi, Muhammad Atique

PMC · DOI: 10.7759/cureus.92595 · Cureus · 2025-09-17

## TL;DR

This case report describes a rare instance of adenoid cystic carcinoma spreading to the liver in a 54-year-old woman.

## Contribution

The novelty lies in documenting a rare hepatic metastasis of ACC alongside pulmonary involvement.

## Key findings

- ACC typically metastasizes to the lungs, bones, and soft tissues, but liver involvement is exceedingly rare.
- A 54-year-old female presented with metastatic ACC in both the lungs and liver.
- This case highlights the need for awareness of unusual metastatic patterns in ACC.

## Abstract

Adenoid cystic carcinoma (ACC) is among the most common primary malignant tumors of the salivary glands. The parotid, submandibular, and minor salivary glands are the predominant sites. Clinical presentation includes a slow-growing mass, often accompanied by pain and paresthesias. Distant spread of the tumor is common - most frequently to the lungs, followed by the bones and other sites such as the liver, brain, and soft tissue. Metastatic ACC involving the liver is exceedingly rare. Given the uncommon occurrence of hepatic metastasis in ACC, we present the case of a 54-year-old female with metastatic involvement of both the lungs and liver.

## Linked entities

- **Diseases:** adenoid cystic carcinoma (MONDO:0004971)

## Full-text entities

- **Diseases:** hepatic metastasis (MESH:D009362), tumor (MESH:D009369), pain (MESH:D010146), paresthesias (MESH:D010292), ACC (MESH:D003528)

## Full text

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## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12534742/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12534742/full.md

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Source: https://tomesphere.com/paper/PMC12534742