# Treatment of a Pediatric Arterial Ischemic Stroke With Tenecteplase

## TL;DR

A 16-year-old boy with a rare stroke was successfully treated with tenecteplase, a drug typically used in adults.

## Contribution

This case report presents a rare and successful use of tenecteplase in treating a pediatric ischemic stroke.

## Key findings

- Tenecteplase was safely administered to a 16-year-old with an arterial ischemic stroke.
- The treatment was effective in resolving the stroke in the middle cerebral artery territory.
- This case highlights the potential for thrombolytic use in pediatric stroke when carefully managed.

## Abstract

Although rare, stroke in children is a worrisome event that can have a profound impact on their development and future health outcomes as adults. While the use of the thrombolytics has become a mainstay of treatment for ischemic stroke in adults at comprehensive stroke centers, neither the efficacy nor the safety of thrombolytics for stroke in children has been established. This is, in part, due to the rarity of the pathology and difficulty in recruitment for clinical studies. Additionally, the more recently adopted thrombolytic, tenecteplase, has even fewer known cases of use in the treatment of ischemic stroke in children. We present a case of a 16-year-old male who presented with an ischemic stroke affecting the middle cerebral artery territory, which was promptly, safely, and successfully treated with tenecteplase.