# Isolated Pancreatic Sarcoidosis Masquerading as Pancreatic Adenocarcinoma: A Case Report

## TL;DR

A 50-year-old man was diagnosed with isolated pancreatic sarcoidosis after being initially suspected of having pancreatic cancer.

## Contribution

This case report highlights the rare occurrence of isolated pancreatic sarcoidosis mimicking pancreatic adenocarcinoma.

## Key findings

- A pancreatic mass was initially suspected to be adenocarcinoma based on CT and PET scans.
- Biopsy results were inconclusive, leading to surgical intervention.
- Pathology confirmed granulomatous inflammation consistent with sarcoidosis.

## Abstract

A 50-year-old man with no known medical history presented with a four-year history of epigastric pain and weight loss. Computed tomography (CT) revealed a mass in the head of the pancreas concerning for adenocarcinoma. The patient twice underwent endoscopic ultrasound (EUS) with biopsy, with inconclusive results. Positron emission tomography (PET) scan revealed localized disease, concerning for malignancy. With no definitive diagnosis or treatment options, and after multidisciplinary discussion, the patient underwent a Whipple procedure. Pathology revealed granulomatous inflammation of the pancreas and surrounding lymph nodes, consistent with sarcoidosis. Here, we present a rare case of isolated pancreatic sarcoidosis masquerading as pancreatic malignancy in a patient without a known history of sarcoidosis.