# Addressing language challenges in bilingual neuropsychological assessments at the South Texas Alzheimer's Disease Research Center (ADRC)

**Authors:** Stephanie Santiago‐Mejias, Gabrielle Hromas, Ashley LaRoche, David A. Gonzalez, Robin C. Hilsabeck, Katya Rascovsky, Silvia Mejia Arango, Amy Werry‐McFarlin, Claudia L. Satizabal, Hector Trevino, Monica Goss, Jennifer Del Bosque, Amaya Seidl, Roberto Garcia, Marialy Salinas Valdez, Angel Velarde, Jessica Zapata, Samantha Gates, Patricia Hernandez, Juan Toranzo, Marucela Uscamayta Ayvar, Denisse Garcia Cisneros, Vanessa M. Young, Sudha Seshadri, Anna Campbell Sullivan

PMC · DOI: 10.1002/alz.70800 · Alzheimer's & Dementia · 2025-10-16

## TL;DR

This paper discusses challenges in assessing bilingual individuals for Alzheimer's research and proposes a structured language evaluation approach to improve test accuracy.

## Contribution

The paper introduces a structured language assessment approach integrating self-reported and objective measures for bilingual cognitive testing.

## Key findings

- Discrepancies between self-reported and objective language proficiency complicate bilingual assessments.
- Systematic language selection can improve test accuracy and data consistency in bilingual evaluations.
- Language assessment guidelines are needed to standardize protocols and enhance research validity.

## Abstract

Neuropsychological assessment of bilingual (English/Spanish) individuals presents challenges that can impact test validity. Language proficiency influences cognitive performance, yet clear guidelines for determining the appropriate test language are lacking. We describe our experiences at the South Texas Alzheimer's Disease Research Center (STAC) in addressing these challenges within the context of National Alzheimer's Coordinating Center (NACC) Uniform Data Set (UDS) assessments and broader Alzheimer's Disease Research Center (ADRC) protocols. We outline steps toward a structured language assessment approach.

We implemented a process to assess language proficiency, integrating self‐reported and objective measures, including the language dominance index (LDI). Case examples illustrate the impact of language on cognitive testing.

Challenges included discrepancies between self‐reported and objective language proficiency, language switching during assessments, and resistance to testing in the dominant language.

Language assessment improves test validity and research consistency. Future efforts should refine bilingual assessment methods and establish standardized protocols.

Systematic test language selection may improve accuracy in bilingual assessments.Discrepancies in reported versus objective language proficiency challenge bilingual assessments.Language evaluation guidelines are needed to improve test validity and data consistency.

Systematic test language selection may improve accuracy in bilingual assessments.

Discrepancies in reported versus objective language proficiency challenge bilingual assessments.

Language evaluation guidelines are needed to improve test validity and data consistency.

## Full-text entities

- **Diseases:** Alzheimer's Disease (MESH:D000544)

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12531422/full.md

## References

56 references — full list in the complete paper: https://tomesphere.com/paper/PMC12531422/full.md

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Source: https://tomesphere.com/paper/PMC12531422