# Case Report: Left bundle branch area pacing in cardiac resynchronization therapy increases conduction velocity

**Authors:** Wenchang Zhang, Leyi Wang, Changjian He, Chunhua Ding

PMC · DOI: 10.3389/fcvm.2025.1620302 · Frontiers in Cardiovascular Medicine · 2025-10-03

## TL;DR

This case report explores the use of left bundle branch area pacing in cardiac resynchronization therapy to improve heart function in a patient with a specific heart condition.

## Contribution

The report provides a detailed case study on the safety and efficacy of LBBAP-CRTD in treating LBBB-induced cardiomyopathy.

## Key findings

- LBBAP-CRTD showed potential in correcting left bundle branch block and improving left ventricular function.
- The case highlights the importance of further research to establish guidelines for LBBAP use in CRT.

## Abstract

Several studies have suggested that the application of left bundle branch area pacing (LBBAP) in cardiac resynchronization therapy (CRT) holds promise as a treatment modality for correcting left bundle branch block (LBBB) while concurrently enhancing left ventricular structure and function. However, it's noteworthy that current guidelines do not provide specific recommendations for the use of left bundle branch area pacing, underscoring the need for additional evidence regarding its safety and efficacy. In this context, we present a case report detailing the utilization of LBBAP-CRTD treatment in a patient with LBBB-induced cardiomyopathy. The investigation encompasses a thorough examination of the efficacy and safety of LBBAP-CRTD, with a particular emphasis on cardiac synchronization parameters. Written consent was obtained from the patient, and this case report adheres to the CARE guideline.

## Linked entities

- **Diseases:** cardiomyopathy (MONDO:0004994)

## Full-text entities

- **Diseases:** LBBB (MESH:D002037), cardiomyopathy (MESH:D009202)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12531258/full.md

## References

22 references — full list in the complete paper: https://tomesphere.com/paper/PMC12531258/full.md

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Source: https://tomesphere.com/paper/PMC12531258