# Septic shock and meningitis caused by Capnocytophaga canimorsus (serovar B) in an immunocompetent patient: case report

**Authors:** Zoja Germuskova, Marc Westerholt, Lukas Frans Ocias

PMC · DOI: 10.1128/asmcr.00076-24 · ASM Case Reports · 2025-01-29

## TL;DR

A healthy man developed fatal septic shock and meningitis from a rare dog-related infection caused by Capnocytophaga canimorsus.

## Contribution

This is the first reported case of a serovar B strain causing severe infection in an immunocompetent individual.

## Key findings

- Capnocytophaga canimorsus serovar B caused septic shock and meningitis in an immunocompetent patient.
- The patient died despite aggressive treatment, highlighting the severity of this infection.
- Whole genome sequencing confirmed the strain as serovar B.

## Abstract

Capnocytophaga canimorsus, a Gram-negative rod found in the commensal oral microflora of dogs, is a rare cause of infection following a dog bite, with severe infections more commonly occurring in asplenic or immunocompromised patients. This is a rare case of septic shock and meningitis with a serovar B strain in an immunocompetent patient who passed away due to the infection.

A previously healthy man in his late 50s with no known immunodeficiencies was admitted to the hospital with fever and cognitive deficits after being bitten by a dog. Capnocytophaga canimorsus grew in his cerebrospinal fluid and blood cultures. Despite aggressive fluid therapy, antibiotics, and intensive care, the patient succumbed to the infection. The strain was later characterized as serovar B using whole genome sequencing.

Even immunocompetent patients are at risk of severe infection caused by Capnocytophaga canimorsus. These infections are an important differential diagnosis in patients presenting with fever following recent dog exposure with serovars A–C being the most common in human clinical isolates.

## Linked entities

- **Diseases:** meningitis (MONDO:0021108)
- **Species:** Capnocytophaga canimorsus (taxon 28188)

## Full-text entities

- **Diseases:** immunodeficiencies (MESH:D007153), infection (MESH:D007239), Septic shock (MESH:D012772), fever (MESH:D005334), cognitive deficits (MESH:D003072), meningitis (MESH:D008580)
- **Species:** Capnocytophaga canimorsus (species) [taxon 28188], Homo sapiens (human, species) [taxon 9606], Canis lupus familiaris (dog, subspecies) [taxon 9615]

## Full text

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12530242/full.md

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Source: https://tomesphere.com/paper/PMC12530242