# Central Giant Cell Granuloma of the Posterior Maxilla

**Authors:** Irukulla Venkata Krishna, G. Venkateswara Reddy, Mohammed Darain Shahid, G.Siva Prasada Reddy, Godvine Sarepally

PMC · DOI: 10.7759/cureus.92340 · Cureus · 2025-09-15

## TL;DR

This paper reports a rare case of a benign jaw tumor in the upper maxilla and emphasizes the importance of combining clinical, imaging, and histological data for accurate diagnosis and effective treatment.

## Contribution

The paper presents a rare clinical case of CGCG in the posterior maxilla and highlights the value of multidisciplinary evaluation for diagnosis.

## Key findings

- CGCG was diagnosed in a 30-year-old female with a posterior maxillary lesion.
- Surgical enucleation, curettage, and peripheral ostectomy were effective in treating the lesion.
- Accurate diagnosis required integration of clinical, radiographic, and histopathological findings.

## Abstract

Central giant cell granuloma (CGCG) is an uncommon, benign, proliferative intraosseous lesion of the jaws with an uncertain etiology. It is more frequently reported in the mandible, whereas maxillary involvement is relatively rare. We present the case of a 30-year-old female patient with a swelling in the right posterior maxilla that had gradually increased in size over a year. Clinical examination revealed a firm, tender, and expansile lesion, while radiographic evaluation demonstrated a well-defined radiolucent lesion associated with the maxillary posterior teeth. Histopathological analysis confirmed the diagnosis of a CGCG. The lesion was surgically treated with enucleation, curettage, and peripheral ostectomy under general anesthesia. This case underscores the significance of correlating clinical, radiological, and histopathological features for the accurate diagnosis of maxillary lesions and highlights surgical management as an effective treatment modality for CGCG.

## Linked entities

- **Diseases:** Central giant cell granuloma (MONDO:0006770)

## Full-text entities

- **Diseases:** CGCG (MESH:D006101), maxillary lesions (MESH:D008439), intraosseous lesion of the (MESH:C564648), swelling (MESH:D004487)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12529891/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12529891/full.md

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Source: https://tomesphere.com/paper/PMC12529891