# Severe Pyogenic Liver Abscess in a Diabetic Patient Presenting With Sepsis and Diabetic Ketoacidosis: A Case Report

## TL;DR

A diabetic patient developed a severe liver abscess with sepsis and diabetic ketoacidosis, requiring intensive treatment and multidisciplinary care to recover.

## Contribution

This case highlights the importance of early diagnosis and multidisciplinary management in complex PLA cases with diabetes and sepsis.

## Key findings

- The patient presented with septic shock and DKA alongside a large pyogenic liver abscess.
- Laparoscopic drainage and targeted antibiotics were necessary for recovery.
- Multidisciplinary care improved outcomes in this high-risk patient.

## Abstract

Pyogenic liver abscess (PLA) is a rare but potentially life-threatening condition, especially in immunocompromised and diabetic patients. Complications such as sepsis and diabetic ketoacidosis (DKA) increase morbidity and mortality among diabetic patients. We report the case of a 50-year-old male patient who presented with fever, confusion, and hypotension. Initial assessment revealed septic shock and DKA. Imaging confirmed a large liver abscess. Despite intensive medical therapy, laparoscopic drainage was required. Culture revealed Klebsiella pneumoniae. The patient required prolonged ICU care, insulin therapy, targeted antibiotics, and multidisciplinary management, after which he gradually improved. Early suspicion and timely intervention are lifesaving in complicated PLA cases. In patients with diabetes and sepsis, multidisciplinary care is crucial for optimizing outcomes.