# Healthcare for individuals with schizophrenia in Taiwan: 10-year national trend analysis

**Authors:** Shen-Yu Tsai, Ming-Shiang Wu, Shi-Heng Wang, Shih-Cheng Liao, Wei J Chen, Chi-Shin Wu

PMC · DOI: 10.1192/bjo.2025.10868 · BJPsych Open · 2025-10-13

## TL;DR

This study analyzed 10 years of healthcare trends for individuals with schizophrenia in Taiwan, showing improvements in treatment and outcomes.

## Contribution

The study provides a comprehensive national trend analysis of schizophrenia care quality in Taiwan from 2010 to 2019.

## Key findings

- Antipsychotic medication usage shifted toward second-generation and long-acting injectable antipsychotics.
- Psychiatric hospitalisations and emergency department visits decreased, while employment rates increased.
- Mortality and suicide rates remained stable despite changes in treatment patterns.

## Abstract

Significant changes in Taiwan’s psychiatric services over recent decades include expansion of community-based clinics and implementation of the Schizophrenia Pay-for-Performance programme.

This study aimed to assess the trend of the quality of healthcare for individuals with schizophrenia, using various indicators of the treatment process and outcomes between 2010 and 2019.

Individuals with schizophrenia were identified using Taiwan’s National Health Insurance claims database. The quality of healthcare for individuals with schizophrenia was assessed using treatment process and outcome indicators, including antipsychotic types, medication adherence, daily dose for antipsychotics and concurrent use of other psychotropic agents. Outcome indicators included all-cause mortality, suicide deaths, psychiatric hospitalisation, emergency department visits and employment status.

Antipsychotic medication usage has shifted towards second-generation antipsychotics (SGAs) and long-acting injectable antipsychotics (LAIs), with declines in first-generation antipsychotics. The percentage of medication adherence declined, while that of individuals with an adequate daily dose increased. Concurrently, anticholinergic and benzodiazepine use decreased while antidepressant and mood stabiliser use increased. Outcome indicators showed no significant change in all-cause mortality or suicide rates over time, but there were reductions in psychiatric hospitalisations and emergency department visits. Employment rates increased overall, particularly in urban areas.

The quality of healthcare for individuals with schizophrenia, as measured by treatment process and outcome indicators, improved alongside changes in Taiwan’s psychiatric services; however, causality cannot be inferred from our findings. Future research should evaluate the effectiveness of psychiatric service policies and continuously monitor healthcare quality to further enhance the lives of individuals with schizophrenia.

## Linked entities

- **Diseases:** schizophrenia (MONDO:0005090)

## Full-text entities

- **Diseases:** psychiatric (MESH:D001523), Schizophrenia (MESH:D012559)
- **Chemicals:** SGAs (-), benzodiazepine (MESH:D001569)

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12529334/full.md

## References

36 references — full list in the complete paper: https://tomesphere.com/paper/PMC12529334/full.md

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Source: https://tomesphere.com/paper/PMC12529334