# Intravenous Thrombolysis for Pediatric Acute Ischemic Stroke **Authors:** Peter B. Sporns, Kartik D. Bhatia, Prakash Muthusami, Carmen Parra-Farinas, Christine K. Fox, Adam A. Dmytriw, Sarah Lee, Jens Fiehler, Todd Abruzzo, Lisa Pabst, Stuart Fraser, Lisa R. Sun, Grégoire Boulouis, Tanja Burkard, Marios Psychogios, Thi Dan Linh Nguyen-Kim, Moritz Wildgruber PMC · DOI: 10.1001/jamanetworkopen.2025.38191 · JAMA Network Open · 2025-10-15 ## TL;DR The study compares the effectiveness and safety of using intravenous thrombolysis in children with acute ischemic stroke versus standard care. ## Contribution This study provides new insights into the outcomes of intravenous thrombolysis in pediatric stroke patients. ## Key findings - Children treated with intravenous thrombolysis showed improved functional outcomes. - No significant increase in adverse events was observed with thrombolysis treatment. ## Abstract This cohort study examines function and safety outcomes among children with pediatric acute ischemic stroke treated with intravenous tissue plasminogen activator compared with standard care. ## Full-text entities - **Diseases:** Acute Ischemic Stroke (MESH:D000083242) ## Full text _Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12529207/full.md ## References 6 references — full list in the complete paper: https://tomesphere.com/paper/PMC12529207/full.md --- Source: https://tomesphere.com/paper/PMC12529207