# Editorial: The need for pragmatic trials in genitourinary oncology

**Authors:** Mieke Van Hemelrijck, Piet Ost, Giorgio Gandaglia

PMC · DOI: 10.3389/fonc.2025.1702188 · Frontiers in Oncology · 2025-10-02

## Full-text entities

- **Genes:** NPEPPS (aminopeptidase puromycin sensitive) [NCBI Gene 9520] {aka AAP-S, MP100, PSA}
- **Diseases:** GU malignancies (MESH:D014565), toxicity (MESH:D064420), depression (MESH:D003866), RCC (MESH:D002292), bladder cancer (MESH:D001749), Prostate Cancer (MESH:D011471), cancer (MESH:D009369), inferior vena cava (IVC) tumour thrombus (MESH:C563013), fatigue (MESH:D005221), renal NETs (MESH:D007680)
- **Chemicals:** REAL (-), nivolumab (MESH:D000077594), ipilimumab (MESH:D000074324)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12529112/full.md

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Source: https://tomesphere.com/paper/PMC12529112