# Aberrant right subclavian artery (ARSA) presenting with esophageal pseudo-neoplastic symptoms, dyspepsia, and hemodynamic findings

**Authors:** Soheil Mirzaei, Zahra Motaghed

PMC · DOI: 10.1016/j.radcr.2025.09.033 · Radiology Case Reports · 2025-10-04

## TL;DR

A rare artery anomaly mimicked a tumor in a patient's esophagus, causing symptoms like indigestion and requiring careful imaging for accurate diagnosis.

## Contribution

Highlights ARSA as a potential cause of pseudo-neoplastic esophageal symptoms and emphasizes the importance of CT angiography in diagnosis.

## Key findings

- CT imaging identified ARSA without a mass in a patient with suspected esophageal malignancy.
- ARSA can cause compressive symptoms like dysphagia and hemodynamic changes such as inter-arm blood pressure differences.
- Accurate imaging is crucial to avoid unnecessary surgery and guide treatment options.

## Abstract

Aberrant right subclavian artery (ARSA) is the most common congenital anomaly of the aortic arch. Though often asymptomatic, it may cause esophageal compression and mimic neoplastic lesions. Accurate diagnosis via CT angiography is essential, especially before thoracic or cervical surgery. A 68-year-old woman presented with dyspepsia, dyspnea, and epigastric pain. Endoscopy revealed a polypoid lesion suggestive of malignancy. CT imaging showed ARSA passing posterior to the esophagus, with no mass detected. Hemodynamic evaluation revealed inter-arm blood pressure discrepancy and bradycardia. ARSA can lead to dysphagia lusoria and other compressive symptoms. Its association with Kommerell’s diverticulum and non-recurrent laryngeal nerve has surgical implications. Treatment options include open, endovascular, and hybrid approaches. ARSA should be considered in patients with atypical esophageal symptoms. Imaging plays a key role in diagnosis and guiding appropriate, individualized treatment.

## Linked entities

- **Diseases:** dyspepsia (MONDO:0002268)

## Full-text entities

- **Diseases:** malignancy (MESH:D009369), epigastric pain (MESH:D010146), congenital anomaly of the aortic arch (MESH:C535542), esophageal compression (MESH:D004941), Kommerell's diverticulum (MESH:D004240), compressive (MESH:D009408), dyspnea (MESH:D004417), bradycardia (MESH:D001919), dyspepsia (MESH:D004415), ARSA (MESH:C535555), dysphagia lusoria (MESH:D003680)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12528888/full.md

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Source: https://tomesphere.com/paper/PMC12528888