# Successful Management of Advanced Olfactory Esthesioneuroblastoma: A Case Report

**Authors:** Chiraz Halwani, Sana Ferchichi, Mariem Messelmani

PMC · DOI: 10.1002/ccr3.71208 · Clinical Case Reports · 2025-10-15

## TL;DR

This case report highlights the effective treatment of advanced olfactory esthesioneuroblastoma using a combination of surgery, radiotherapy, and chemotherapy.

## Contribution

The paper presents a successful clinical case emphasizing the importance of multimodal treatment and long-term follow-up for this rare tumor.

## Key findings

- Multimodal treatment improves outcomes in advanced esthesioneuroblastoma.
- Long-term follow-up is essential to detect recurrences and manage complications.
- Multidisciplinary coordination is key to managing this complex tumor.

## Abstract

Early imaging and biopsy are crucial for diagnosing esthesioneuroblastoma. Multimodal treatment—endoscopic or combined surgery, adjuvant radiotherapy, and selective chemotherapy—offers the best outcomes. Long‐term follow‐up is essential to detect recurrences and manage complications like optic neuritis. Multidisciplinary coordination optimizes care in this anatomically complex, recurrent‐prone tumor.

## Linked entities

- **Diseases:** esthesioneuroblastoma (MONDO:0016029), optic neuritis (MONDO:0005885)

## Full-text entities

- **Diseases:** tumor (MESH:D009369), optic neuritis (MESH:D009902), Olfactory Esthesioneuroblastoma (MESH:D018304)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12528537/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12528537/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12528537/full.md

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Source: https://tomesphere.com/paper/PMC12528537