# Multidisciplinary protocols are an important part of enhanced recovery after major lower extremity amputation

**Authors:** Christian Campat, Leigh Ann O’Banion

PMC · DOI: 10.3389/fsurg.2025.1637121 · Frontiers in Surgery · 2025-10-02

## TL;DR

This paper discusses how using structured multidisciplinary protocols can improve recovery and outcomes for patients undergoing major lower extremity amputation.

## Contribution

The paper introduces tailored ERAS-based multidisciplinary protocols for MLEA to reduce complications and improve recovery.

## Key findings

- ERAS protocols can reduce complications in MLEA patients.
- Multidisciplinary care improves functional recovery and promotes equity in outcomes.
- Standardized care pathways enhance perioperative management for MLEA.

## Abstract

Major lower extremity amputation (MLEA) remains a high-risk procedure with significant implications for patient morbidity, mortality, and long-term functional independence. Optimizing outcomes for this vulnerable population requires a comprehensive, multidisciplinary approach guided by evidence-based perioperative care pathways. Enhanced Recovery After Surgery (ERAS) protocols offer a structured framework to improve recovery trajectories by standardizing key elements of care. This review examines the application of ERAS principles to the MLEA population, synthesizing current literature on preoperative assessment and patient selection, multimodal analgesia, early mobilization strategies, and coordinated post-discharge planning. By integrating findings from consensus statements and pilot studies, we demonstrate how tailored ERAS-based multidisciplinary protocols can reduce complications, enhance functional recovery, and promote equity in outcomes. The development and implementation of such structured care pathways represent a critical step toward improving the standard of care for patients undergoing major lower extremity amputation.

## Full-text entities

- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

32 references — full list in the complete paper: https://tomesphere.com/paper/PMC12528115/full.md

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Source: https://tomesphere.com/paper/PMC12528115