# Case Report: Rare primary bronchogenic acinic cell carcinoma in a pediatric patient

**Authors:** Yuxing Sun, Jun Zhou, Jiaojiao Zhu, Ming Li, Shiwu Yang, Songtao Bin, Li Tan

PMC · DOI: 10.3389/fonc.2025.1640216 · Frontiers in Oncology · 2025-10-02

## TL;DR

A rare case of bronchogenic acinic cell carcinoma in a young child is reported, highlighting its unusual presentation and successful treatment through surgery.

## Contribution

This case report adds to the limited literature on primary bronchogenic acinic cell carcinoma in pediatric patients.

## Key findings

- A 3-year-old boy was diagnosed with primary bronchogenic acinic cell carcinoma after imaging and bronchoscopy.
- Surgical resection led to a recurrence-free outcome over 18 months of follow-up.
- Non-specific symptoms and radiological features can lead to misdiagnosis in pediatric cases.

## Abstract

Acinic cell carcinoma (AciCC) is an uncommon tumor of the salivary glands, with primary bronchogenic cases being particularly rare, especially in children. This report presents a case of a 3-year and 11-month-old boy who exhibited symptoms of cough and fever. Contrast-enhanced CT imaging revealed a solid mass in the right upper lung lobe accompanied by atelectasis, with poor bronchial visualization and no abnormal enhancement. Bronchoscopy identified a tumor obstructing the right upper lobe bronchial orifice. Surgical resection was performed, and histopathological analysis confirmed acinic cell carcinoma without lymph node involvement. The patient remained recurrence-free during an 18-month follow-up. Pediatric primary bronchial AciCC is exceptionally rare and typically manifests with non-specific symptoms. Radiological findings such as solid lung lesions or atelectasis may lead to misdiagnosis as pneumonia. However, complete surgical excision generally yields favorable outcomes.

## Linked entities

- **Diseases:** acinic cell carcinoma (MONDO:0004965), pneumonia (MONDO:0005249)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** pneumonia (MESH:D011014), cough (MESH:D003371), atelectasis (MESH:D001261), tumor (MESH:D009369), AciCC (MESH:D018267), fever (MESH:D005334), lung lesions (MESH:D008171)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12527867/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12527867/full.md

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Source: https://tomesphere.com/paper/PMC12527867