# Zoonosis: a comprehensive database of zoonotic pathogens

**Authors:** Boyuan Zhang, Dan Liu, Weiwen Wang, Xiaoqiang Li, Yifei Xie, Huitong Li, Hongmei Zhou, Jianshuai Gao, Hui Jiang, Xuezheng Fan, Jiabo Ding, Qingchun Shen, Xizheng Ma

PMC · DOI: 10.1093/database/baaf062 · Database: The Journal of Biological Databases and Curation · 2025-10-15

## TL;DR

Zoonosis is a new database tracking zoonotic pathogens to help prevent disease spread between animals and humans.

## Contribution

Zoonosis introduces a comprehensive, globally accessible database of zoonotic pathogens with integrated analysis tools.

## Key findings

- Zoonosis contains over 4500 samples from more than 60 countries.
- The database includes pathogens like Brucella, Mycobacterium tuberculosis, and Bacillus anthracis.
- It provides tools for visualizing and analyzing zoonotic disease data.

## Abstract

Emerging infectious diseases pose a significant threat to global public health and economic security, with zoonoses accounting for a substantial proportion. Livestock such as cattle and sheep are critical reservoirs for zoonotic pathogens and play a key role in transmitting these pathogens to humans and other animals, including dogs and wildlife, due to their close interaction with diverse populations. In this study, we introduce Zoonosis (http://zoonosis.cn/zoonosis/), a comprehensive database that integrates data on pathogens, including Brucella, Mycobacterium tuberculosis, and Bacillus anthracis. Currently, Zoonosis integrates over 4500 samples from more than 60 countries, with a total data volume of 1.8TB, providing a global perspective on zoonotic disease distribution. Equipped with user-friendly visualization and analysis tools, Zoonosis enables rapid biological data interpretation, aiding disease diagnosis and prevention. This resource supports virology, zoology, and epidemiology experts in monitoring cross-species transmissions and mitigating future zoonotic outbreaks.

Database URL: http://zoonosis.cn/zoonosis/

## Full-text entities

- **Diseases:** TB (MESH:D014390), Zoonosis (MESH:D015047), infectious diseases (MESH:D003141)
- **Species:** Canis lupus familiaris (dog, subspecies) [taxon 9615], Mycobacterium tuberculosis (species) [taxon 1773], Bos taurus (bovine, species) [taxon 9913], Ovis aries (domestic sheep, species) [taxon 9940], Bacillus anthracis (anthrax bacterium, species) [taxon 1392], Homo sapiens (human, species) [taxon 9606], Brucella (genus) [taxon 234]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12527251/full.md

## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC12527251/full.md

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Source: https://tomesphere.com/paper/PMC12527251